Date published: 2026-2-27

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TIM-4 Activators

T-cell Immunoglobulin and Mucin-Domain Containing-4 (TIM-4) is a protein that plays a crucial role in the immune response, particularly in the clearance of apoptotic cells. Several compounds could influence the function of TIM-4 indirectly through related pathways or cellular processes. TIM-4 Activators represent a class of chemicals that can influence the function of TIM-4. These compounds can indirectly influence the function of TIM-4 through their effects on related immune pathways.

Chemicals such as PMA, Ionomycin, Lipopolysaccharide, Poly I:C, CpG ODN, Imiquimod, Resiquimod, Gardiquimod, R848, CL097, Pam3CSK4, and FSL-1 can potentially influence TIM-4 function through their effects on immune cell activation and the modulation of immune responses. The effects of these chemicals on TIM-4 function are context-dependent and may vary based on the immune environment and other biochemical parameters.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

Phorbol 12-myristate 13-acetate (PMA) is a potent activator of Protein Kinase C (PKC) that can indirectly influence TIM-4 by modulating the activity of immune cells such as macrophages.

Ionomycin, free acid

56092-81-0sc-263405
sc-263405A
1 mg
5 mg
$96.00
$264.00
2
(2)

Ionomycin, a calcium ionophore, can indirectly influence TIM-4 by triggering calcium-dependent signaling pathways in immune cells.

Lipopolysaccharide, E. coli O55:B5

93572-42-0sc-221855
sc-221855A
sc-221855B
sc-221855C
10 mg
25 mg
100 mg
500 mg
$98.00
$171.00
$425.00
$1560.00
12
(2)

Lipopolysaccharide (LPS), a component of the outer membrane of gram-negative bacteria, can stimulate immune responses and may influence the expression of TIM-4 in immune cells.

Polyinosinic acid - polycytidylic acid sodium salt, double-stranded

42424-50-0sc-204854
sc-204854A
10 mg
100 mg
$139.00
$663.00
2
(1)

Poly I:C, a synthetic analog of double-stranded RNA, can trigger immune responses and may influence the expression of TIM-4 in immune cells.

Imiquimod

99011-02-6sc-200385
sc-200385A
100 mg
500 mg
$67.00
$284.00
6
(1)

Imiquimod, a toll-like receptor 7 agonist, can stimulate immune responses and may influence the expression of TIM-4 in immune cells.

R-848

144875-48-9sc-203231
sc-203231A
sc-203231B
sc-203231C
5 mg
25 mg
100 mg
500 mg
$102.00
$306.00
$510.00
$1559.00
12
(1)

Resiquimod, a toll-like receptor 7 and 8 agonist, can stimulate immune responses and may influence the expression of TIM-4 in immune cells.

Gardiquimod

1020412-43-4sc-221663
sc-221663A
sc-221663B
sc-221663C
sc-221663D
sc-221663E
sc-221663F
25 mg
50 mg
100 mg
250 mg
5 g
10 g
25 g
$157.00
$282.00
$516.00
$1177.00
$20138.00
$32779.00
$70753.00
1
(1)

Gardiquimod, a toll-like receptor 7 agonist, can stimulate immune responses and may influence the expression of TIM-4 in immune cells.

CL097

1026249-18-2sc-507394
5 mg
$135.00
(0)

CL097, a toll-like receptor 7 and 8 agonist, can stimulate immune responses and may influence the expression of TIM-4 in immune cells.

Pam3Cys-Ser-(Lys)4, Hydrochloride

112208-00-1sc-507471
2 mg
$550.00
(0)

Pam3CSK4, a toll-like receptor 1 and 2 agonist, can stimulate immune responses and may influence the expression of TIM-4 in immune cells.