Date published: 2026-5-16

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Pam3Cys-Ser-(Lys)4, Hydrochloride (CAS 112208-00-1)

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Datasheets
Alternate Names:
Pam3Cys-Ser-(Lys)4, Hydrochloride, (S)-[2,3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys4-OH, 3HCl, P3CSK4, 3HCl, Pam3Cys-SK4, 3HCl, Pam3CSK4, TLR1/TLR2 Agonist I
CAS Number:
112208-00-1
Molecular Weight:
1619.61
Molecular Formula:
C81H156N10O133HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Pam3Cys-Ser-(Lys)4, Hydrochloride (CAS 112208-00-1) References

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  2. Effect of pro-inflammatory stimuli on mucin expression and inhibition by secretory leucoprotease inhibitor.  |  Griffin, S., et al. 2007. Cell Microbiol. 9: 670-9. PMID: 17026478
  3. Protein-bound polysaccharide K augments IL-2 production from murine mesenteric lymph node CD4+ T cells by modulating T cell receptor signaling.  |  Asai, H., et al. 2008. Cancer Immunol Immunother. 57: 1647-55. PMID: 18343922
  4. Surface RANKL of Toll-like receptor 4-stimulated human neutrophils activates osteoclastic bone resorption.  |  Chakravarti, A., et al. 2009. Blood. 114: 1633-44. PMID: 19546479
  5. Toll-like receptor 2 ligand-induced protection against bacterial endophthalmitis.  |  Kumar, A., et al. 2010. J Infect Dis. 201: 255-63. PMID: 19995266
  6. Amniotic fluid angiopoietin-1, angiopoietin-2, and soluble receptor tunica interna endothelial cell kinase-2 levels and regulation in normal pregnancy and intraamniotic inflammation-induced preterm birth.  |  Buhimschi, CS., et al. 2010. J Clin Endocrinol Metab. 95: 3428-36. PMID: 20410222
  7. TLR2 mediates the innate response of retinal Muller glia to Staphylococcus aureus.  |  Shamsuddin, N. and Kumar, A. 2011. J Immunol. 186: 7089-97. PMID: 21602496
  8. Toll-like receptor 2 ligand pretreatment attenuates retinal microglial inflammatory response but enhances phagocytic activity toward Staphylococcus aureus.  |  Kochan, T., et al. 2012. Infect Immun. 80: 2076-88. PMID: 22431652
  9. Retinal photoreceptor expresses toll-like receptors (TLRs) and elicits innate responses following TLR ligand and bacterial challenge.  |  Singh, PK. and Kumar, A. 2015. PLoS One. 10: e0119541. PMID: 25767877
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pam3Cys-Ser-(Lys)4, Hydrochloride, 2 mg

sc-507471
2 mg
$550.00