TEN1 Activators
The chemical class named TEN1 Activators includes compounds that potentially induce the expression or activity of TEN1. These activators mainly target pathways related to telomere maintenance, DNA repair, and cellular aging. They function through various mechanisms, such as modulation of telomerase activity, activation of DNA repair enzymes, and influencing pathways related to oxidative stress and cellular senescence.
Compounds like Cycloastragenol and Astragaloside IV are known for their potential effects on telomerase activation, which is closely connected to telomere maintenance, a key aspect of TEN1's function. Antioxidants like EGCG, Resveratrol, and Quercetin may impact telomere dynamics indirectly through their roles in cellular stress responses and DNA repair mechanisms. Rapamycin and other compounds that modulate aging pathways could also affect TEN1 expression by influencing the cellular environment in which telomeres function. Understanding how these activators influence TEN1 expression and activity is important in the context of telomere biology and genome stability. Insights into the regulation of TEN1 can provide valuable knowledge about telomere maintenance mechanisms and their impact on cellular aging and genomic integrity.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Astragaloside IV | 84687-43-4 | sc-257103 | 20 mg | $57.00 | 1 | |
Astragaloside IV, like cycloastragenol, may influence TEN1 activity by impacting telomerase activity and telomere maintenance. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol might enhance TEN1 expression through its role in activating sirtuins, which are linked to DNA repair and telomere stability. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $110.00 $150.00 $220.00 $300.00 $600.00 | 4 | |
NMN, a precursor of NAD+, could affect TEN1 expression by influencing sirtuin activity and cellular stress responses related to telomeres. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 may modulate TEN1 expression indirectly through its regulatory roles in DNA repair and cellular aging processes. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc, an essential mineral, might play a role in TEN1 expression by supporting DNA synthesis and repair mechanisms. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin may affect TEN1 expression through its role in modulating cellular stress response pathways and enhancing DNA repair mechanisms. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, an mTOR inhibitor, could influence TEN1 expression by modulating cellular aging processes and potentially impacting telomere dynamics. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane, by activating Nrf2, may impact TEN1 expression as it is involved in cellular defense mechanisms related to DNA damage response. | ||||||
Fisetin | 528-48-3 | sc-276440 sc-276440A sc-276440B sc-276440C sc-276440D | 50 mg 100 mg 500 mg 1 g 100 g | $52.00 $79.00 $104.00 $156.00 $2913.00 | 7 | |
Fisetin may enhance TEN1 expression through its roles in cellular signaling, particularly in pathways related to aging and DNA repair. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin could modulate TEN1 expression through its broad impact on cellular signaling pathways, including those related to DNA repair and telomere stability. | ||||||