TECK inhibitors belong to a distinct chemical class that has garnered significant attention in the field of molecular research due to their unique properties and potential implications for various biological processes. The term "TECK" refers to Thymidine Kinase, a key enzyme involved in the regulation of DNA synthesis. Inhibitors targeting Thymidine Kinase have become a subject of interest for their potential to modulate cellular proliferation, as the enzyme plays a crucial role in the synthesis of DNA precursors. The chemical structure of TECK inhibitors is characterized by its specificity towards the active site of Thymidine Kinase, which enables them to interfere with the enzymatic activity and disrupt the normal progression of DNA synthesis.
TECK inhibitors often feature a core scaffold with functional groups that facilitate interaction with the Thymidine Kinase active site. The design of these inhibitors involves careful consideration of molecular properties to enhance binding affinity and selectivity. Researchers aim to optimize the pharmacokinetic profile and potency of TECK inhibitors, seeking to achieve effective modulation of Thymidine Kinase activity. The exploration of TECK inhibitors extends beyond their immediate impact on DNA synthesis, as researchers investigate potential applications in various cellular processes and pathways.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A specific inhibitor of phosphoinositide 3-kinases (PI3Ks), which can indirectly reduce kinase activity downstream of PI3K signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A selective inhibitor of mitogen-activated protein kinase kinase (MEK), which can indirectly inhibit kinases that are regulated by the MAPK/ERK pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A specific inhibitor of p38 MAP kinase, which indirectly modulates kinases involved in the p38 MAPK signaling pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of c-Jun N-terminal kinase (JNK), which can alter kinase activity associated with the JNK signaling pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, which can indirectly affect kinase signaling within the mTOR pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A potent PI3K inhibitor, which can indirectly influence kinase activity mediated through PI3K-dependent pathways. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
A protein kinase C inhibitor, which may indirectly affect kinase activity within PKC-regulated pathways. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor, which can indirectly modulate kinase activity associated with the Rho kinase pathway. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
A Src family kinase inhibitor, which indirectly impacts kinases that are activated by Src family proteins. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
An inhibitor of NF-kB activation, which can indirectly affect kinase activity within NF-kB signaling pathways. |