Tctex5 Activators
Protein Phosphatase 1 Regulatory Inhibitor Subunit 11 (PPP1R11) is a protein encoded by the PPP1R11 gene in humans. This protein serves a significant role as a regulatory subunit of Protein Phosphatase 1 (PP1), a crucial enzyme responsible for dephosphorylation, the removal of phosphate groups from proteins. Dephosphorylation is a key mechanism in controlling various cellular processes, including cell division, protein synthesis, and glycogen metabolism.
PPP1R11 acts as an inhibitor of PP1. It binds to the catalytic subunit of PP1, inhibiting its phosphatase activity and thus inhibiting the dephosphorylation of target proteins. This inhibition ensures that proteins requiring a phosphate group for their function retain it, allowing them to carry out their respective roles within the cell.Interestingly, PPP1R11 has a demonstrated role in the immune response. It's known to inhibit the dephosphorylation of transcription factor Stat1, a central player in the interferon response pathway, which is vital for antiviral immunity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Okadaic acid is a potent inhibitor of protein phosphatases PP1 and PP2A, and its use might indirectly affect PPP1R11-mediated regulation. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Calyculin A, like okadaic acid, inhibits PP1 and PP2A, potentially influencing PPP1R11 function indirectly. | ||||||
Cantharidin | 56-25-7 | sc-201321 sc-201321A | 25 mg 100 mg | $89.00 $279.00 | 6 | |
Cantharidin inhibits PP2A and might have indirect effects on PP1 and PPP1R11. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
cAMP is a secondary messenger that can modulate protein phosphatase activity and potentially influence PPP1R11 function. | ||||||
Endothall | 145-73-3 | sc-201325 sc-201325A | 20 mg 100 mg | $49.00 $203.00 | 1 | |
Endothall is an inhibitor of PP2A and could indirectly affect PPP1R11 by altering PP1 dynamics. | ||||||
D-erythro-Sphingosine | 123-78-4 | sc-3546 sc-3546A sc-3546B sc-3546C sc-3546D sc-3546E | 10 mg 25 mg 100 mg 1 g 5 g 10 g | $90.00 $194.00 $510.00 $2448.00 $9384.00 $15300.00 | 2 | |
Sphingosine can act as a signaling molecule and may influence protein phosphatase activity, potentially affecting PPP1R11. | ||||||
PIK-75, hydrochloride | 372196-77-5 | sc-296089 sc-296089A | 1 mg 5 mg | $29.00 $124.00 | ||
BIM-1 is a PKC inhibitor, and by modulating PKC activity, it might indirectly influence PPP1R11. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a broad-spectrum kinase inhibitor that could indirectly impact PPP1R11 through various signaling pathways. | ||||||