TBL1XR1 Activators
The chemical class TBL1XR1 Activators encompasses a wide range of compounds that indirectly influence the activity of TBL1XR1, a protein involved in gene transcription and nuclear receptor signaling. These compounds primarily act through their ability to modulate gene transcription or to influence the signaling pathways of nuclear receptors.
Retinoic acid, estradiol, dexamethasone, tamoxifen, mifepristone, and rosiglitazone represent a subset of these activators acting through nuclear receptor signaling. These compounds are known to interact with various nuclear receptors, including the retinoic acid receptor, estrogen receptor, glucocorticoid receptor, and PPARγ. Their activity on these receptors can alter gene transcription, indirectly influencing the activity of TBL1XR1, which is known to interact with nuclear receptors. On the other hand, ATRA, JQ1, SAHA, Trichostatin A, 5-Azacytidine, and EGCG represent a group of TBL1XR1 activators that primarily modulate gene transcription. These compounds include inhibitors of the BET family of bromodomain proteins and histone deacetylases, as well as a nucleoside analogue of cytidine that inhibits DNA methylation.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid is a metabolite of vitamin A that mediates the functions of vitamin A required for growth and development. It can activate nuclear receptors and influence gene transcription, possibly affecting TBL1XR1 activity. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Estradiol is a steroid and estrogen sex hormone. It modulates the estrogen receptor, a nuclear receptor that TBL1XR1 is known to interact with. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone is a glucocorticoid that is known to interact with the glucocorticoid receptor, which can influence nuclear receptor signaling and gene transcription, possibly affecting TBL1XR1 activity. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $256.00 | 18 | |
Tamoxifen is an antagonist of the estrogen receptor in breast tissue. Its modulation of estrogen receptor activity could indirectly affect TBL1XR1. | ||||||
Mifepristone | 84371-65-3 | sc-203134 | 100 mg | $60.00 | 17 | |
Mifepristone is a glucocorticoid receptor antagonist. By affecting glucocorticoid receptor signaling, it could indirectly affect TBL1XR1 activity. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
Rosiglitazone is an anti-diabetic drug that works as a PPARγ agonist. This activation of PPARγ may influence TBL1XR1 activity indirectly. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
JQ1 is a small molecule inhibitor of the BET family of bromodomain proteins. It can influence gene transcription, which indirectly could affect TBL1XR1. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
SAHA is a histone deacetylase (HDAC) inhibitor that can modulate gene transcription, potentially influencing TBL1XR1 activity. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is another HDAC inhibitor that can influence gene transcription, potentially affecting TBL1XR1 activity. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a nucleoside analogue of cytidine that can inhibit DNA methylation and affect gene transcription, possibly affecting TBL1XR1 activity. | ||||||