Tas2r143 Inhibitors
Tas2r143 inhibitors are a class of chemical compounds designed to target and inhibit the activity of the Tas2r143 receptor, a member of the taste receptor family known as the TAS2R (bitter taste receptor) family. Tas2r143 is primarily expressed in taste receptor cells located on the tongue and plays a role in the detection of bitter compounds. This receptor is part of a larger group of G-protein-coupled receptors (GPCRs) that initiate a signal transduction cascade upon binding to specific bitter-tasting molecules, leading to the perception of bitterness. By inhibiting Tas2r143, these compounds block the receptor's ability to respond to bitter stimuli, effectively reducing or eliminating the activation of the signaling pathways that lead to bitter taste perception.
Research on Tas2r143 inhibitors provides insights into the molecular mechanisms of taste perception, particularly how bitter compounds are detected and processed by the sensory system. These inhibitors allow scientists to explore the specific role of Tas2r143 in detecting a wide range of bitter compounds, contributing to a better understanding of the diversity and specificity of the TAS2R family. Additionally, Tas2r143 inhibitors help researchers dissect the signaling pathways associated with taste perception, shedding light on how G-protein-coupled receptors like Tas2r143 influence cellular responses to external stimuli. These inhibitors are valuable tools for studying the complex interactions between bitter taste receptors and their ligands, providing a deeper understanding of the biochemical and molecular processes that govern taste sensation and sensory communication within the body.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol may inhibit taste receptor type 2 member 143 expression by modulating sirtuin activity, leading to changes in chromatin structure that could affect the transcription of TAS2R143 gene. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin may inhibit taste receptor type 2 member 143 expression by modulating various signaling pathways involved in gene expression regulation, thus affecting the transcription of TAS2R143. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin gallate may inhibit taste receptor type 2 member 143 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R143 gene expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein may inhibit taste receptor type 2 member 143 expression by interfering with estrogen receptor signaling, which could modulate downstream transcriptional regulation of the TAS2R143 gene. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $97.00 $212.00 $500.00 | 11 | |
Kaempferol may inhibit taste receptor type 2 member 143 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R143 gene expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin may inhibit taste receptor type 2 member 143 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R143 gene expression. | ||||||
Naringenin | 480-41-1 | sc-219338 | 25 g | $245.00 | 11 | |
Naringenin may inhibit taste receptor type 2 member 143 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R143 gene expression. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $32.00 $210.00 $720.00 $1128.00 $2302.00 $3066.00 $5106.00 | 22 | |
Apigenin may inhibit taste receptor type 2 member 143 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R143 gene expression. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $26.00 $50.00 $99.00 $150.00 $1887.00 | 40 | |
Luteolin may inhibit taste receptor type 2 member 143 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R143 gene expression. | ||||||
Fisetin | 528-48-3 | sc-276440 sc-276440A sc-276440B sc-276440C sc-276440D | 50 mg 100 mg 500 mg 1 g 100 g | $51.00 $77.00 $102.00 $153.00 $2856.00 | 7 | |
Fisetin may inhibit taste receptor type 2 member 143 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R143 gene expression. | ||||||