TAF II p105 Inhibitors
TAF II p105 inhibitors encompass a range of chemicals that interact with the protein or its associated pathways to modulate its activity. These inhibitors affect TAF II p105 indirectly by interfering with cellular processes or signaling pathways that are crucial for the protein's normal function. The chemicals listed above represent diverse chemical classes, including polyphenols like curcumin and resveratrol, which can disrupt TAF II p105's interaction with other transcription factors or its role in stress response pathways, respectively. Isoflavonoids like genistein, flavonoids like quercetin, and catechins like EGCG have structures that allow them to influence kinase pathways and other signaling cascades that can alter the phosphorylation state of TAF II p105, thus impacting its transcriptional regulatory functions.
Many of the chemicals that inhibit TAF II p105 are naturally occurring compounds found in foods and plants, such as the diterpene triepoxide triptolide, which is known to interfere with the NF-kB pathway, or the flavonolignan silibinin, which acts on various signal transduction pathways. Alkaloids like berberine affect metabolic signaling, while organosulfur compounds such as sulforaphane modulate antioxidant response pathways, both influencing TAF II p105 activity. Wogonin, another flavone, affects signaling pathways crucial to the transcriptional activity of TAF II p105. Lastly, synthetic compounds like LY294002, a small-molecule inhibitor of the PI3K/Akt pathway, demonstrate the breadth of chemical interactions that can indirectly modulate the function of TAF II p105.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is a biologically active polyphenolic compound found in turmeric. It can inhibit the transcriptional activation ability of TAF II p105 by interfering with its binding to other transcription factors. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a natural phenol found in grapes, can disrupt signaling pathways that involve TAF II p105, particularly those linked to cellular stress responses, thereby impacting its function. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, an isoflavonoid derived from soy products, can modulate kinase pathways that phosphorylate TAF II p105, altering its activity and potentially its interaction with the basal transcription machinery. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid with the ability to modulate various signal transduction pathways. It can influence TAF II p105 indirectly by affecting its phosphorylation state and interaction with other transcription factors. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, the main catechin in green tea, can interfere with pathways that activate TAF II p105, impacting its role in transcriptional regulation. | ||||||
Indirubin | 479-41-4 | sc-201531 sc-201531A | 5 mg 25 mg | $114.00 $525.00 | 4 | |
Indirubin, a molecule derived from indigo plants, can inhibit cyclin-dependent kinases that may modulate the activity of TAF II p105, thereby influencing its function. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide, a diterpene triepoxide derived from the Thunder God Vine, can inhibit the transcriptional activity of TAF II p105 by interfering with the NF-kB pathway. | ||||||
Silybin | 22888-70-6 | sc-202812 sc-202812A sc-202812B sc-202812C | 1 g 5 g 10 g 50 g | $55.00 $114.00 $206.00 $714.00 | 6 | |
Silibinin, a flavonolignan from milk thistle, can act on signal transduction pathways that include TAF II p105, altering its activation and thereby its function in transcription. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine, an isoquinoline alkaloid found in many plants, can modulate TAF II p105 activity indirectly through interference with metabolic signaling pathways. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane, a compound within the isothiocyanate group of organosulfur compounds found in cruciferous vegetables, can impact TAF II p105 through the modulation of antioxidant response elements linked pathways. | ||||||