Date published: 2025-10-25

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T2R07 Inhibitors

T2R07 inhibitors are chemicals or compounds that can interfere with the function of the T2R07 protein, specifically by inhibiting its bitter taste receptor activity. The bitter taste receptor, encoded by the T2R07 gene, is responsible for detecting and signaling the presence of bitter compounds in the oral cavity. By binding to this receptor, inhibitors can prevent its activation and subsequent downstream signaling pathways involved in bitter taste perception. Several chemicals can act as direct inhibitors of T2R07 by binding to the bitter taste receptor and blocking its activation. Caffeine, denatonium benzoate, quinine, saccharin, Sodium N-cyclohexylsulfamate, Amiloride • HCl, diphenhydramine hydrochloride, probenecid, cyclizine hydrochloride, quinidine sulfate, Bitrex (Denatonium saccharide), and N-Phenylthiourea are all examples of T2R07 inhibitors. Caffeine, denatonium benzoate, quinine, saccharin, Sodium N-cyclohexylsulfamate, and Denatonium saccharide are bitter compounds that can competitively bind to the bitter taste receptor, preventing the activation of T2R07. By occupying the receptor binding site, these inhibitors inhibit the perception of bitter taste stimuli and the downstream signaling pathways associated with T2R07. Amiloride • HCl, diphenhydramine hydrochloride, cyclizine hydrochloride, and Quinidine sulfate dihydrate are compounds that can block the bitter taste receptor. They bind to the receptor and prevent its activation, inhibiting the perception of bitter taste stimuli and the associated signaling pathways. Probenecid is a chemical that can interfere with the bitter taste receptor signaling pathways. It disrupts the normal functioning of the receptor, leading to the inhibition of bitter taste perception. N-Phenylthiourea is a bitter compound that can directly bind to the bitter taste receptor, blocking its activation. This inhibits the perception of bitter taste stimuli and the downstream signaling pathways associated with T2R07. Overall, T2R07 inhibitors are chemicals or compounds that can interfere with the function of the bitter taste receptor, inhibiting the perception of bitter taste stimuli and the associated signaling pathways. These inhibitors can be bitter compounds that competitively bind to or block the bitter taste receptor, preventing its activation and subsequent signaling.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Denatonium saccharide

90823-38-4sc-214864
sc-214864A
sc-214864B
1 g
25 g
100 g
$56.00
$106.00
$320.00
(0)

Bitrex, also known as Denatonium saccharide, is a bitter compound commonly used as a taste aversive agent. It can inhibit T2R07 by binding to the bitter taste receptor and blocking its activation. This prevents the perception of bitter taste stimuli and inhibits the signaling pathways associated with T2R07.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
5 g
100 g
250 g
1 kg
5 kg
$32.00
$66.00
$95.00
$188.00
$760.00
13
(1)

Caffeine is a methylxanthine compound that can inhibit T2R07 by blocking the bitter taste receptor. It binds to the receptor and prevents the activation of downstream signaling pathways, thereby inhibiting the response to bitter taste stimuli.

Denatonium benzoate

3734-33-6sc-234525
sc-234525A
sc-234525B
sc-234525C
sc-234525D
1 g
5 g
25 g
100 g
250 g
$31.00
$46.00
$138.00
$464.00
$903.00
(1)

Denatonium benzoate is a bitter compound commonly used as a taste aversive agent. It can inhibit T2R07 by binding to the bitter taste receptor and blocking its activation. This prevents the perception of bitter taste stimuli and inhibits the signaling pathways associated with T2R07.

Quinine

130-95-0sc-212616
sc-212616A
sc-212616B
sc-212616C
sc-212616D
1 g
5 g
10 g
25 g
50 g
$77.00
$102.00
$163.00
$347.00
$561.00
1
(0)

Quinine is a natural compound found in the bark of the cinchona tree. It can inhibit T2R07 by binding to the bitter taste receptor and blocking its activation. This prevents the perception of bitter taste stimuli and inhibits the downstream signaling pathways associated with T2R07.

Saccharin

81-07-2sc-212902
sc-212902A
sc-212902B
100 mg
1 g
10 g
$173.00
$235.00
$286.00
(0)

Saccharin is an artificial sweetener that can inhibit T2R07 by competitively binding to the bitter taste receptor. By occupying the receptor binding site, saccharin prevents the activation of T2R07 and inhibits the downstream signaling pathways involved in bitter taste perception.

Sodium N-cyclohexylsulfamate

139-05-9sc-253592
250 g
$64.00
(0)

Sodium N-cyclohexylsulfamate is an artificial sweetener that can inhibit T2R07 by competitively binding to the bitter taste receptor. Similar to saccharin, Sodium N-cyclohexylsulfamate occupies the receptor binding site, preventing the activation of T2R07 and inhibiting the associated signaling pathways.

Amiloride • HCl

2016-88-8sc-3578
sc-3578A
25 mg
100 mg
$22.00
$56.00
6
(2)

Amiloride • HCl is a diuretic that can inhibit T2R07 by blocking the bitter taste receptor. It binds to the receptor and prevents its activation, thereby inhibiting the perception of bitter taste stimuli and the downstream signaling pathways associated with T2R07.

Diphenhydramine hydrochloride

147-24-0sc-204729
sc-204729A
sc-204729B
10 g
25 g
100 g
$51.00
$82.00
$122.00
4
(1)

Diphenhydramine hydrochloride is an antihistamine that can inhibit T2R07 by blocking the bitter taste receptor. It binds to the receptor and prevents its activation, inhibiting the perception of bitter taste stimuli and the associated signaling pathways.

Probenecid

57-66-9sc-202773
sc-202773A
sc-202773B
sc-202773C
1 g
5 g
25 g
100 g
$27.00
$38.00
$98.00
$272.00
28
(2)

Probenecid is a compound used to research gout and increase the effectiveness of certain antibiotics. It can inhibit T2R07 by interfering with the bitter taste receptor signaling pathways. Probenecid disrupts the normal functioning of the receptor, leading to the inhibition of bitter taste perception.

Cyclizine Hydrochloride

303-25-3sc-391816
1 g
$300.00
(0)

Cyclizine hydrochloride is an antihistamine that can inhibit T2R07 by blocking the bitter taste receptor. It binds to the receptor and prevents its activation, inhibiting the perception of bitter taste stimuli and the associated signaling pathways.