SUHW1 Activators

Zinc finger protein 280A (ZNF280A) is a member of the zinc finger protein family, which is one of the largest families of transcription factors in eukaryotic organisms. Transcription factors are proteins that bind to specific DNA sequences and regulate the transcription of genetic information from DNA to messenger RNA. Zinc finger proteins are characterized by their finger-like protrusions, which are structured by zinc ion coordination with cysteine and histidine residues, forming a stable domain that can interact with DNA.

The specific structure of ZNF280A allows it to bind to DNA at particular sites, influencing the transcriptional activity of associated genes. The "zinc finger" motif acts as a DNA-binding domain which typically recognizes and binds to specific sequences of DNA, thereby positioning ZNF280A to either promote or inhibit the transcription of nearby genes. These actions can have numerous downstream effects on cellular functions such as growth, differentiation, and apoptosis.ZNF280A is involved in regulatory networks within the cell and can interact with other proteins, including other transcription factors and co-regulators, to exert its effects on gene expression. This allows ZNF280A to integrate into various signaling pathways, responding to cellular cues and environmental signals to modulate gene expression appropriately.