Staphylococcus aureus Activators
Staphylococcus aureus Activators comprise a diverse group of chemical entities that augment the functional activity of Staphylococcus aureus through various intracellular signaling mechanisms. Forskolin indirectly increases the activity of Staphylococcus aureus by boosting cAMP levels, which activate PKA and may promote phosphorylation cascades beneficial to Staphylococcus aureus function. A23187 and Calcium Chloride act by raising intracellular calcium concentrations, leading to the activation of calcium-dependent protein kinases that can enhance the activity of the Staphylococcus aureus. The PKC activator PMA and the phosphodiesterase inhibitor IBMX contribute to the activation of Staphylococcus aureus by supporting phosphorylation processes that modulate the protein's activity, emphasizing the complex interplay between different signaling molecules and the pathways they influence.
Furthermore, the PI3K inhibitors LY294002 and Wortmannin, along with the MEK inhibitors PD98059 and U0126, serve to shift cellular signaling in favor of enhancing Staphylococcus aureus activity. By inhibiting certain kinases, these compounds reduce the competitive interference from other signaling routes, allowing Staphylococcus aureus-related pathways to become more prominent. Genistein and SB203580 specifically inhibit tyrosine kinases and p38 MAPK, respectively, which may relieve inhibitory phosphorylation events on proteins that interact with Staphylococcus aureus, thereby indirectly enhancing its activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin raises intracellular cAMP, which could indirectly enhance Staphylococcus aureus activity by activating cAMP-dependent pathways that interact with Staphylococcus aureus. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187 increases intracellular calcium, potentially enhancing Staphylococcus aureus activity by activating calcium-dependent kinases and signaling pathways associated with the bacterial protein. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a PKC activator that could facilitate Staphylococcus aureus activity through PKC-mediated phosphorylation events that enhance its biological function. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX, a phosphodiesterase inhibitor, could elevate cAMP and enhance Staphylococcus aureus activity through PKA activation and subsequent phosphorylation of proteins that interact with Staphylococcus aureus. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that might upregulate pathways enhancing Staphylococcus aureus activity by altering signaling dynamics that indirectly affect the protein. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059, a MEK inhibitor, might enhance Staphylococcus aureus activity by decreasing competitive ERK/MAPK signaling, thus favoring pathways that lead to its activation. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $66.00 $262.00 | 1 | |
By increasing intracellular calcium, Calcium Chloride may enhance Staphylococcus aureus activity through the activation of calcium-dependent signaling mechanisms. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
Engaging with G-protein coupled receptors, Sphingosine-1-phosphate might enhance Staphylococcus aureus activity by promoting signaling pathways that interact with the protein. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein inhibits tyrosine kinases, potentially enhancing Staphylococcus aureus activity by reducing competitive phosphorylation events. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 inhibits p38 MAPK, potentially enhancing Staphylococcus aureus activity by lessening competitive signaling pathways. | ||||||