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Staphylococcus aureus 抗体 (704): sc-58038

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说明书
  • Staphylococcus aureus 抗体 704 是小鼠单克隆 IgG3Staphylococcus aureus抗体, 在1篇文献中引用,规格为100 µg/ml
  • 针对紫外线灭活的Staphylococcus aureus细胞的抗体
  • 推荐用于检测Staphylococcus aureus, Protein A-negative Staph. aureus and Staph. epidermidis(由ELISA提供; 不会与 Corynebacteria species, Streptococcus species or Mycoplasma species产生交联反应
  • 关于如何获取Staphylococcus aureus (704): sc-58038免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG3 BP-HRP是Staphylococcus aureus Antibody (704). 的首选辅助检测试剂,该试剂现与Staphylococcus aureus Antibody (704) 搭配使用(请参阅下面的订购信息)。

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金黄色葡萄球菌抗体(704)是一种小鼠单克隆 IgG3 抗体,可通过酶联免疫吸附试验(ELISA)检测金黄色葡萄球菌蛋白。抗金黄色葡萄球菌抗体 (704) 是一种非结合型单克隆同型抗体。金黄色葡萄球菌(Staphylococcus aureus)是一种革兰氏阳性球菌,通常存在于人体皮肤和鼻腔中,在共生和致病相互作用中发挥着重要作用。这种细菌会产生β-内酰胺酶,这种酶能降解青霉素的β-内酰胺环,从而使金黄色葡萄球菌对包括青霉素和头孢菌素在内的多种抗生素产生耐药性。金黄色葡萄球菌会引起各种感染,从轻微的皮肤病到肺炎、脑膜炎、心内膜炎、败血症和中毒性休克综合症(TSS)等严重疾病。分泌的外毒素毒性休克综合征毒素-1(TSST-1)通过诱导主要组织相容性复合体(MHC)II 类分子与 T 细胞受体的非特异性结合,导致广泛的 T 细胞活化和免疫失调,从而成为一种关键的致病因子。这种失调会导致以 B 细胞亢进为特征的各种自身免疫和过敏性疾病。TSS 症状可迅速升级,表现为高烧、低血压、乏力和意识模糊,有可能发展为昏迷、昏迷和多器官衰竭等严重并发症。金黄色葡萄球菌能够逃避免疫反应并导致严重的健康问题,这就强调了使用金黄色葡萄球菌单克隆抗体(704)进行有效检测和监测的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Staphylococcus aureus 抗体 (704) 参考文献:

  1. 金黄色葡萄球菌流行病学的变化?  |  Chambers, HF. 2001. Emerg Infect Dis. 7: 178-82. PMID: 11294701
  2. 感染含有 vanA 抗性基因的耐万古霉素金黄色葡萄球菌。  |  Chang, S., et al. 2003. N Engl J Med. 348: 1342-7. PMID: 12672861
  3. 月经期妇女中产生中毒性休克综合征毒素 1 的金黄色葡萄球菌的流行率以及这种超抗原抗体的存在。  |  Parsonnet, J., et al. 2005. J Clin Microbiol. 43: 4628-34. PMID: 16145118
  4. 针对中毒性休克综合征毒素-1 设计的高亲和力 T 细胞受体的特征。  |  Buonpane, RA., et al. 2005. J Mol Biol. 353: 308-21. PMID: 16171815
  5. 细菌超级抗原 TSST-1 削弱了糖皮质激素和钙调磷酸酶抑制剂对抗中性粒细胞胞浆抗体相关性脉管炎和肾病患者外周血单核细胞增殖的抑制作用。  |  Hirano, T., et al. 2006. Int Immunopharmacol. 6: 924-34. PMID: 16644478
  6. 新生儿葡萄球菌皮肤烫伤综合征:一种不常见的噬菌体类型导致的大规模爆发。  |  Curran, JP. and Al-Salihi, FL. 1980. Pediatrics. 66: 285-90. PMID: 6447271
  7. 葡萄球菌中毒性休克综合征毒素-1 对 B 细胞凋亡的不同影响  |  Hofer, MF., et al. 1996. Proc Natl Acad Sci U S A. 93: 5425-30. PMID: 8643591
  8. 超级抗原中毒性休克综合征毒素-1能诱导CD40配体的表达并调节IgE的同型转换。  |  Jabara, HH. and Geha, RS. 1996. Int Immunol. 8: 1503-10. PMID: 8921429
  9. 对万古霉素敏感性降低的耐甲氧西林金黄色葡萄球菌临床菌株。  |  Hiramatsu, K., et al. 1997. J Antimicrob Chemother. 40: 135-6. PMID: 9249217

订购信息

产品名称产品编号规格价格数量收藏夹

Staphylococcus aureus 抗体 (704)

sc-58038
100 µg/ml
$316.00

Staphylococcus aureus (704): m-IgG3 BP-HRP 套装

sc-550378
100 µg Ab; 40 µg BP
$354.00

Another Q: what is a recommended dilution range of sc 58038 for ELISA and do you also sell a ? rat or other species such as rabbit ? monoclonal to mouse IgG3 and if so does this second antibody have a reporter such as HRP or AP? Thanks, Paddy

Asked by: paddy
Thank you for your question. For ELISA we recommend performing a titration to find the optimal concentration to use. You can find our recommended protocol here: https://www.scbt.com/scbt/resources/protocols/elisa-assays We do not sell rabbit antibodies at this time. You can use any anti-mouse secondary conjugated to HRP or AP for your ELISA assay.
Answered by: Tech Service
Date published: 2019-04-09

Hi are all your S aureus antibodies labeled with an Alexa dye and specifically A-488?

Asked by: paddy
Thank you for your question. No, neither of our S. aureus antibodies are labeled with an alexa dye. If you wish to order it conjugated, please contact our Special Orders Department to see if this is a possibility.
Answered by: Tech Service
Date published: 2019-04-09

What is the total volume provided of Staphylococcus aureus (704): sc-58038 monoclonal antibody?

Asked by: Cweed
Thank you for your question. This antibody is provided as 100 µg in 1 ml total volume.
Answered by: Technical Support
Date published: 2017-03-07
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Rated 5 out of 5 by from Can be used for immunofluorescenceThis antibody has been used for immunofluorescence in published research. -SCBT QC
Date published: 2023-09-14
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Staphylococcus aureus 抗体 (704) is rated 4.5 out of 5 by 2.
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