Ssa1 Activators
The category of Ssa1 Activators encompasses a range of chemical compounds that, while not directly activating Ssa1, influences its activity through modulation of cellular stress response pathways and protein homeostasis mechanisms. Ssa1, as a heat shock protein, plays a critical role in responding to cellular stress and aiding in protein folding and stabilization. The first group of these compounds includes molecules known to induce cellular stress or affect protein homeostasis, such as 17-AAG, Quercetin, Curcumin, Resveratrol, N-Acetylcysteine, and EGCG. These substances, by triggering stress responses or modulating signaling pathways, can indirectly lead to the upregulation of Ssa1. For example, HSP90 inhibitors like 17-AAG can increase the cellular demand for chaperone activity, leading to an increased expression of Hsp70 family proteins, including Ssa1.
Another significant group comprises compounds and conditions that directly induce a stress response in cells, such as Salicylic Acid, Caffeine, Sodium Arsenite, MG132, and oxidative stress inducers like Hydrogen Peroxide. These substances can trigger cellular mechanisms that lead to the enhanced expression of stress response proteins such as Ssa1. For instance, oxidative stress inducers can activate cellular defense mechanisms, including the upregulation of heat shock proteins as part of the response.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $67.00 $156.00 | 16 | |
HSP90 inhibitor, potentially upregulating HSP70 proteins like Ssa1 in response to increased cellular stress. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid known to induce heat shock response, potentially enhancing Ssa1 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Influences multiple cellular pathways, including stress responses, potentially modulating Ssa1 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Known to affect gene expression and stress response pathways, potentially influencing Ssa1. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
An antioxidant, potentially modulating cellular stress responses and affecting Ssa1 activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Affects various signaling pathways, potentially influencing Ssa1 activity in stress response. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $47.00 $94.00 $119.00 | 3 | |
Can induce heat shock response, potentially impacting Ssa1 expression. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Modulates various cellular processes, including stress responses, potentially affecting Ssa1. | ||||||
Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $108.00 $780.00 | 3 | |
Induces cellular stress response, potentially upregulating Ssa1 expression. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Proteasome inhibitor, can induce stress response, potentially enhancing Ssa1 activity. | ||||||