SRP68 Activators
SRP68 activators are a category of chemicals that indirectly influence the activity of the SRP68 protein. These compounds primarily act by modulating protein synthesis, a process intricately linked to SRP68 function. By manipulating the protein synthesis machinery, these chemicals can indirectly affect the role of SRP68 in the translocation of proteins across the endoplasmic reticulum membrane. Within this class, there are inhibitors of protein synthesis. For instance, activators disrupt protein synthesis by blocking the translocation step, which is a crucial phase where SRP68 is actively involved. Similarly,activators of this class obstruct elongation at the ribosome level, which can indirectly influence the SRP68 pathway.
Additionally, the group includes mTOR inhibitors. The mTOR pathway is a central regulator of cell growth and protein synthesis. For instance, activators can indirectly influence SRP68 functionality by modulating the protein synthesis machinery. Similarly, activators also form a complex with FKBP12 to inhibit mTOR, a protein kinase that plays a pivotal role in protein synthesis and cell proliferation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide inhibits protein synthesis in eukaryotes by blocking the translocation step in protein synthesis, thus potentially affecting SRP68-associated processes. | ||||||
Emetine | 483-18-1 | sc-470668 sc-470668A sc-470668B sc-470668C | 1 mg 10 mg 50 mg 100 mg | $440.00 $900.00 $1400.00 $2502.00 | ||
Emetine is an inhibitor of protein biosynthesis in eukaryotic cells by inhibiting elongation at the ribosome level, potentially affecting the SRP68 pathway. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $42.00 $214.00 $832.00 $66.00 | 394 | |
Puromycin causes premature chain termination during translation, leading to the production of incomplete proteins, potentially affecting SRP68-associated processes. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin is an antibiotic that inhibits protein synthesis by blocking peptide bond formation, potentially affecting the processes associated with SRP68. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $52.00 $125.00 $182.00 | 11 | |
Harringtonine inhibits protein synthesis by preventing the addition of new amino acids to the growing peptide chain during translation, potentially affecting SRP68-associated processes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin binds to FKBP12 and directly inhibits mTOR, a protein kinase involved in protein synthesis and proliferation, potentially affecting SRP68-associated processes. | ||||||
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $245.00 | 7 | |
Torin1 is a potent inhibitor of mTORC1 and mTORC2, key players in the control of cell growth and protein synthesis, potentially affecting SRP68 functionality. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $163.00 $352.00 | 12 | |
AZD8055 is a potent inhibitor of mTOR kinase, which plays central roles in cellular growth and protein synthesis, potentially affecting SRP68-associated processes. | ||||||
PP242 | 1092351-67-1 | sc-301606A sc-301606 | 1 mg 5 mg | $57.00 $172.00 | 8 | |
PP242 is a selective mTOR inhibitor with potential effects on the protein synthesis machinery, thus potentially affecting SRP68-associated processes. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin has multiple targets including mTOR and p70S6 kinase that are involved in protein synthesis, potentially affecting SRP68-associated processes. | ||||||