Date published: 2026-2-14

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SPBP Activators

SPBP Activators, short for Specific Protein-Binding Peptide Activators, represent a fascinating class of molecules with unique chemical properties and a distinct role in modulating cellular processes. These compounds are characterized by their ability to interact with specific proteins within the cell, thereby regulating various biological activities. SPBP Activators typically consist of small, organic molecules that possess a high affinity for particular protein targets. Through their binding interactions, SPBP Activators can influence protein conformation, stability, or activity, leading to downstream effects on cellular functions.

The mechanism of action of SPBP Activators relies on their structural compatibility with the target protein's binding site. These molecules are meticulously designed to fit into the active site of the target protein, often through non-covalent interactions such as hydrogen bonding, electrostatic forces, or van der Waals forces. This binding event triggers a series of intracellular signaling cascades, which can either enhance or inhibit the function of the target protein. SPBP Activators play a crucial role in the field of basic research, enabling scientists to probe and dissect the intricate pathways and networks that underlie cellular processes. Their ability to selectively modulate specific proteins allows for the exploration of protein function and signaling pathways, contributing to our understanding of cell biology and molecular mechanisms. Despite their valuable role in elucidating cellular processes, it's important to note that SPBP Activators should be used with caution, as their interactions with target proteins can have profound effects on cellular physiology.

SEE ALSO...

Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin activates adenylate cyclase, increasing cAMP levels, which in turn can activate PKA. PKA may then phosphorylate SPBP, enhancing its transcriptional regulatory activities.

IBMX

28822-58-4sc-201188
sc-201188B
sc-201188A
200 mg
500 mg
1 g
$260.00
$350.00
$500.00
34
(1)

IBMX is a non-selective inhibitor of phosphodiesterases, elevating cAMP and cGMP levels, potentially enhancing SPBP activity by promoting PKA-mediated phosphorylation.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA activates protein kinase C (PKC), which could phosphorylate SPBP or associated proteins, thereby influencing SPBP's transcriptional regulation capabilities.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$78.00
$270.00
80
(4)

Ionomycin is a calcium ionophore that increases intracellular calcium levels, potentially activating calcineurin or other calcium-dependent kinases that could phosphorylate SPBP.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG is a kinase inhibitor that might enhance SPBP activity by inhibiting kinases that negatively regulate SPBP, thereby reducing their inhibitory effects.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

LY294002 is a PI3K inhibitor, which could shift signaling pathways towards those that activate SPBP or its associated regulators, thus enhancing SPBP activity.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

U0126 is a MEK inhibitor, which may lead to compensatory activation of alternative pathways that could enhance SPBP's functional activity.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

SB203580 is a p38 MAPK inhibitor, which could indirectly enhance SPBP activity by modulating the cellular response to stress or inflammation, pathways where SPBP may be involved.

Okadaic Acid

78111-17-8sc-3513
sc-3513A
sc-3513B
25 µg
100 µg
1 mg
$291.00
$530.00
$1800.00
78
(4)

Okadaic Acid is a potent inhibitor of protein phosphatases PP1 and PP2A, which could lead to increased phosphorylation levels of SPBP, thereby enhancing its activity.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$99.00
$259.00
36
(2)

Anisomycin is a protein synthesis inhibitor, which can activate stress-activated protein kinases (SAPKs), potentially enhancing SPBP activity through stress response pathways.