SPBP Activators, short for Specific Protein-Binding Peptide Activators, represent a fascinating class of molecules with unique chemical properties and a distinct role in modulating cellular processes. These compounds are characterized by their ability to interact with specific proteins within the cell, thereby regulating various biological activities. SPBP Activators typically consist of small, organic molecules that possess a high affinity for particular protein targets. Through their binding interactions, SPBP Activators can influence protein conformation, stability, or activity, leading to downstream effects on cellular functions.
The mechanism of action of SPBP Activators relies on their structural compatibility with the target protein's binding site. These molecules are meticulously designed to fit into the active site of the target protein, often through non-covalent interactions such as hydrogen bonding, electrostatic forces, or van der Waals forces. This binding event triggers a series of intracellular signaling cascades, which can either enhance or inhibit the function of the target protein. SPBP Activators play a crucial role in the field of basic research, enabling scientists to probe and dissect the intricate pathways and networks that underlie cellular processes. Their ability to selectively modulate specific proteins allows for the exploration of protein function and signaling pathways, contributing to our understanding of cell biology and molecular mechanisms. Despite their valuable role in elucidating cellular processes, it's important to note that SPBP Activators should be used with caution, as their interactions with target proteins can have profound effects on cellular physiology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which in turn can activate PKA. PKA may then phosphorylate SPBP, enhancing its transcriptional regulatory activities. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX is a non-selective inhibitor of phosphodiesterases, elevating cAMP and cGMP levels, potentially enhancing SPBP activity by promoting PKA-mediated phosphorylation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC), which could phosphorylate SPBP or associated proteins, thereby influencing SPBP's transcriptional regulation capabilities. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, potentially activating calcineurin or other calcium-dependent kinases that could phosphorylate SPBP. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a kinase inhibitor that might enhance SPBP activity by inhibiting kinases that negatively regulate SPBP, thereby reducing their inhibitory effects. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor, which could shift signaling pathways towards those that activate SPBP or its associated regulators, thus enhancing SPBP activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is a MEK inhibitor, which may lead to compensatory activation of alternative pathways that could enhance SPBP's functional activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a p38 MAPK inhibitor, which could indirectly enhance SPBP activity by modulating the cellular response to stress or inflammation, pathways where SPBP may be involved. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Okadaic Acid is a potent inhibitor of protein phosphatases PP1 and PP2A, which could lead to increased phosphorylation levels of SPBP, thereby enhancing its activity. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin is a protein synthesis inhibitor, which can activate stress-activated protein kinases (SAPKs), potentially enhancing SPBP activity through stress response pathways. | ||||||