Date published: 2026-5-5

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Sox-11 Activators

Sox-11 Activators belong to a distinctive chemical class that primarily focuses on molecular regulators known as transcription factors. Transcription factors are essential proteins responsible for modulating gene expression, orchestrating the intricate dance of genes turning on and off in response to various cellular signals and environmental cues. Sox-11, in particular, is a member of the Sox (SRY-related HMG-box) family of transcription factors, which play pivotal roles in embryonic development, tissue differentiation, and cell fate determination. Sox-11 itself is highly conserved across species and is found in many tissues and cell types, including the nervous system, where it is involved in neurogenesis and neuronal maturation.

Sox-11 activators, as the name suggests, are compounds or molecules that have the unique capability to enhance the transcriptional activity of Sox-11. These activators can bind to specific regions of the Sox-11 protein or its associated regulatory elements within the genome, ultimately leading to an increase in the expression of target genes controlled by Sox-11. The activation of Sox-11 is a critical step in various developmental processes, as it governs the expression of genes involved in cell differentiation, tissue formation, and cell fate determination. Understanding and manipulating the activity of Sox-11 through its activators is of significant interest in the field of molecular biology and genetics, as it provides insights into the intricate mechanisms underlying cellular development and has the ability to impact various research areas, such as regenerative medicine, tissue engineering, and developmental biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid can regulate gene expression through retinoic acid receptors, which may influence Sox-11 expression in differentiation pathways.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This cytidine analog can cause DNA demethylation, potentially leading to the activation of silenced genes, including possibly Sox-11.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

A polyphenol found in green tea that may modulate gene expression and has been shown to affect several biological pathways, possibly including Sox-11.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium can impact glycogen synthase kinase 3 (GSK-3) signaling, which may upregulate Wnt signaling and potentially Sox-11 expression.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

This compound activates adenylate cyclase and increases cAMP levels, which can lead to changes in gene expression, including that of Sox-11.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA activates protein kinase C, which can lead to altered transcription factor activity and possibly increased Sox-11 expression.

Dibutyryl-cAMP

16980-89-5sc-201567
sc-201567A
sc-201567B
sc-201567C
20 mg
100 mg
500 mg
10 g
$47.00
$136.00
$492.00
$4552.00
74
(7)

As a cAMP analog, it can mimic the effect of cAMP in the cell and potentially induce gene expression changes including Sox-11.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

A glucocorticoid that can affect transcription factor activity and may thereby influence Sox-11 expression levels.

Dimethyl Sulfoxide (DMSO)

67-68-5sc-202581
sc-202581A
sc-202581B
100 ml
500 ml
4 L
$31.00
$117.00
$918.00
136
(6)

Often used as a solvent, it can also modulate differentiation pathways in cells that may include upregulation of Sox-11.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$63.00
$182.00
8
(1)

As an estrogen, it can interact with estrogen receptors and potentially modulate gene expression, including that of Sox-11.