Sox-11 Activators belong to a distinctive chemical class that primarily focuses on molecular regulators known as transcription factors. Transcription factors are essential proteins responsible for modulating gene expression, orchestrating the intricate dance of genes turning on and off in response to various cellular signals and environmental cues. Sox-11, in particular, is a member of the Sox (SRY-related HMG-box) family of transcription factors, which play pivotal roles in embryonic development, tissue differentiation, and cell fate determination. Sox-11 itself is highly conserved across species and is found in many tissues and cell types, including the nervous system, where it is involved in neurogenesis and neuronal maturation.
Sox-11 activators, as the name suggests, are compounds or molecules that have the unique capability to enhance the transcriptional activity of Sox-11. These activators can bind to specific regions of the Sox-11 protein or its associated regulatory elements within the genome, ultimately leading to an increase in the expression of target genes controlled by Sox-11. The activation of Sox-11 is a critical step in various developmental processes, as it governs the expression of genes involved in cell differentiation, tissue formation, and cell fate determination. Understanding and manipulating the activity of Sox-11 through its activators is of significant interest in the field of molecular biology and genetics, as it provides insights into the intricate mechanisms underlying cellular development and has the ability to impact various research areas, such as regenerative medicine, tissue engineering, and developmental biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid can regulate gene expression through retinoic acid receptors, which may influence Sox-11 expression in differentiation pathways. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This cytidine analog can cause DNA demethylation, potentially leading to the activation of silenced genes, including possibly Sox-11. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol found in green tea that may modulate gene expression and has been shown to affect several biological pathways, possibly including Sox-11. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium can impact glycogen synthase kinase 3 (GSK-3) signaling, which may upregulate Wnt signaling and potentially Sox-11 expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
This compound activates adenylate cyclase and increases cAMP levels, which can lead to changes in gene expression, including that of Sox-11. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C, which can lead to altered transcription factor activity and possibly increased Sox-11 expression. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
As a cAMP analog, it can mimic the effect of cAMP in the cell and potentially induce gene expression changes including Sox-11. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
A glucocorticoid that can affect transcription factor activity and may thereby influence Sox-11 expression levels. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $31.00 $117.00 $918.00 | 136 | |
Often used as a solvent, it can also modulate differentiation pathways in cells that may include upregulation of Sox-11. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
As an estrogen, it can interact with estrogen receptors and potentially modulate gene expression, including that of Sox-11. | ||||||