Sox-11 Inhibitors
Sox-11 inhibitors belong to a class of chemical compounds designed to target and modulate the activity of the Sox-11 transcription factor. Sox-11, short for SRY-related HMG-box 11, is a member of the Sox (Sry-related high mobility group box) family of transcription factors that play crucial roles in regulating gene expression and cell fate determination. Sox-11 itself is known to be involved in various biological processes, including embryonic development, tissue differentiation, and neural development. It is highly expressed in specific cell types, particularly in neuronal tissues, where it plays a pivotal role in regulating the development and maintenance of neural cells.
The primary objective of Sox-11 inhibitors is to interfere with the function of Sox-11 by binding to it or modulating its activity, thereby influencing downstream gene expression and cellular processes. These inhibitors can function through various mechanisms, such as blocking Sox-11's binding to DNA, disrupting protein-protein interactions, or promoting its degradation. The precise mode of action may vary among different compounds within this class. Researchers are particularly interested in Sox-11 inhibitors for their ability to manipulate cell differentiation and developmental pathways, making them valuable tools for studying fundamental biological processes and influencing cell fate in a controlled manner.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor that has been shown to alter chromatin structure and modulate gene expression, potentially leading to the inhibition of Sox-11. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Suberoylanilide Hydroxamic Acid, another histone deacetylase inhibitor, may modify chromatin accessibility and influence gene expression patterns, potentially downregulating Sox-11 expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
5-Aza-2′-Deoxycytidine is a cytidine analog used to induce DNA hypomethylation, which can affect the expression of numerous genes, potentially including Sox-11. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium Butyrate acts as a histone deacetylase inhibitor, influencing chromatin structure and gene expression, which could lead to changes in Sox-11 expression. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic Acid has histone deacetylase inhibitory activity, potentially affecting chromatin remodeling and gene expression, including the expression of Sox-11. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol has been shown to modulate various signaling pathways and influence gene expression, potentially leading to the inhibition of Sox-11 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has antioxidant properties, and it has been shown to modulate the expression of various genes, potentially including Sox-11. | ||||||
hydroxychloroquine | 118-42-3 | sc-507426 | 5 g | $56.00 | 1 | |
Hydroxychloroquine Sulfate can affect cellular processes and signaling pathways, potentially leading to changes in gene expression, including the expression of Sox-11. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, a kinase involved in cell growth and proliferation, potentially influencing the expression of various genes, including Sox-11. | ||||||