SIRT3 Activators
Common SIRT3 Activators include, but are not limited to Quercetin CAS 117-39-5, Curcumin CAS 458-37-7, (-)-Epigallocatechin Gallate CAS 989-51-5, 1,1-Dimethylbiguanide, Hydrochloride CAS 1115-70-4 and 3,4-Dihydroxyphenyl Ethanol CAS 10597-60-1.
SIRT3 Activators constitute a distinct group of chemical compounds known for their capability to modulate the activity of sirtuin 3 (SIRT3) proteins. This chemical class operates by interacting with and enhancing the signaling pathways associated with SIRT3, a member of the sirtuin family of proteins with essential roles in regulating cellular metabolism, energy balance, and oxidative stress responses. SIRT3 is recognized for its involvement in diverse biological processes, including mitochondrial function, stress adaptation, and cellular longevity.
SIRT3 Activators exert their influence through specific molecular interactions that could amplify the downstream effects of SIRT3-mediated signaling, contributing to the fine-tuning of mitochondrial function, cellular energy production, and maintenance of redox homeostasis. The intricate mechanisms through which SIRT3 Activators impact SIRT3-related pathways remain a focus of ongoing scientific investigation, offering insights into the complex interplay between cellular processes and metabolic regulation. The specific ways in which this chemical class engages with SIRT3 highlight its significance in unraveling the complexities of cellular metabolism and enhancing our understanding across various scientific domains.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenol found in red grapes and red wine, resveratrol is known to activate SIRT3 expression. It has been linked to improved mitochondrial function and increased longevity | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
NR is a form of vitamin B3 that boosts NAD+ levels in cells, leading to SIRT3 activation. Increased NAD+ levels support mitochondrial function and enhance cellular metabolism | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid abundant in fruits and vegetables. It can stimulate SIRT3 expression and protect against oxidative stress by enhancing mitochondrial antioxidant defenses | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Found in turmeric, curcumin is known for its anti-inflammatory and antioxidant properties. It can activate SIRT3 expression, which in turn contributes to improved mitochondrial function | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a polyphenol present in green tea. It has been shown to increase SIRT3 levels, promoting mitochondrial biogenesis and enhancing cellular antioxidant capacity | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
A widely used diabetes agent in research, metformin can induce SIRT3 expression. It enhances insulin sensitivity and has been linked to improved metabolic health | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
ALA is an antioxidant that can stimulate SIRT3 expression. It supports mitochondrial function and may have protective effects against age-related diseases | ||||||
3,4-Dihydroxyphenyl Ethanol | 10597-60-1 | sc-202887 | 10 mg | $112.00 | 6 | |
Found in olive oil, hydroxytyrosol can induce SIRT3 expression. It contributes to the well-known health benefits of the Mediterranean diet | ||||||
Sodium Salicylate | 54-21-7 | sc-3520 sc-3520A sc-3520B sc-3520C | 1 g 25 g 500 g 1 kg | $10.00 $26.00 $82.00 $139.00 | 8 | |
Salicylate, a compound found in plants and also the active ingredient in aspirin, can increase SIRT3 levels. It has been associated with anti-inflammatory effects and potential benefits for mitochondrial function | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine is a natural compound found in various plants. It can activate SIRT3 expression and has been studied for its potential to improve insulin sensitivity and metabolic health | ||||||