Date published: 2025-12-19

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Silg111 Inhibitors

Silg111 inhibitors are a class of chemical compounds specifically designed to target and block the activity of the Silg111 protein. Silg111 is a protein that likely plays a role in cellular signaling pathways, though its exact function may still be under investigation or emerging in research. Proteins like Silg111 are often involved in regulating cell communication, intracellular signaling, or gene expression, contributing to a variety of cellular processes such as differentiation, growth, or immune response. Inhibitors of Silg111 are developed to interfere with its function by binding to critical regions of the protein, which may prevent it from interacting with other signaling molecules or from participating in the pathways it regulates.

The development of Silg111 inhibitors involves studying the structural characteristics of the protein to identify key domains or binding sites essential for its function. Structural biology techniques, including X-ray crystallography, molecular docking, and computational modeling, help identify regions of the protein where inhibitors can effectively bind and block its activity. These inhibitors are designed to fit specifically into these functional domains, ensuring that they prevent Silg111 from interacting with other proteins or from modulating downstream signaling pathways. After synthesis, these inhibitors are evaluated through biochemical assays to test their binding affinity, specificity, and impact on the protein's function. By inhibiting Silg111, researchers aim to gain insights into the biological role of this protein and the pathways it influences, contributing to a better understanding of cellular signaling networks and how individual proteins like Silg111 regulate essential processes within cells. This research enhances knowledge about the intricate molecular mechanisms that govern cell behavior and communication.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

ABT-199

1257044-40-8sc-472284
sc-472284A
sc-472284B
sc-472284C
sc-472284D
1 mg
5 mg
10 mg
100 mg
3 g
$116.00
$330.00
$510.00
$816.00
$1632.00
10
(0)

BCL-2 inhibitor that promotes apoptosis, potentially counteracting the anti-apoptotic effects mediated by HAX-1.

Obatoclax Mesylate

803712-79-0sc-364221
sc-364221A
5 mg
10 mg
$94.00
$138.00
(1)

BCL-2 family protein inhibitor, could indirectly affect HAX-1's role in cell survival by modulating apoptosis pathways.

ABT 737

852808-04-9sc-207242
2.5 mg
$200.00
54
(3)

A BH3 mimetic that inhibits BCL-2, BCL-xL, and BCL-w, potentially influencing apoptosis mechanisms related to HAX-1 activity.

Z-VAD-FMK

187389-52-2sc-3067
500 µg
$74.00
256
(6)

A broad-spectrum caspase inhibitor, could indirectly influence apoptosis pathways where HAX-1 might play a role.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$94.00
$349.00
114
(2)

SERCA pump inhibitor that induces ER stress and calcium release, potentially affecting HAX-1 related calcium signaling.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$169.00
$299.00
66
(3)

Induces ER stress by inhibiting N-linked glycosylation, potentially impacting cellular processes involving HAX-1.

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$62.00
$90.00
$299.00
$475.00
$1015.00
$2099.00
69
(5)

Inhibits the mitochondrial permeability transition pore, possibly affecting mitochondrial functions related to HAX-1.

2-APB

524-95-8sc-201487
sc-201487A
20 mg
100 mg
$27.00
$52.00
37
(1)

Modulates IP3 receptors and store-operated calcium entry, potentially impacting HAX-1 associated calcium signaling.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$56.00
$260.00
$980.00
163
(3)

Proteasome inhibitor, could stabilize proteins involved in apoptosis and cell survival, indirectly affecting HAX-1's function.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$132.00
$1064.00
115
(2)

Another proteasome inhibitor, might influence cellular pathways and protein stability related to HAX-1.