Signal Transduction
Items 171 to 180 of 264 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
DL-PPMP | 149022-18-4 | sc-205655 sc-205655A | 5 mg 25 mg | $73.00 $292.00 | 4 | |
DL-PPMP is a potent inhibitor of glycosylation processes, impacting signal transduction by disrupting the interaction between glycoproteins and their receptors. Its unique ability to interfere with specific enzyme pathways alters the kinetics of cellular signaling cascades, particularly those involved in cell adhesion and migration. By modulating the glycan structures on cell surfaces, DL-PPMP influences receptor-ligand interactions, ultimately affecting cellular communication and response mechanisms. | ||||||
MAFP | 188404-10-6 | sc-203440 | 5 mg | $215.00 | 4 | |
MAFP is a selective inhibitor that modulates signal transduction by targeting specific lipid signaling pathways. It interacts with key enzymes involved in phospholipid metabolism, altering the dynamics of second messenger production. This disruption affects the activation of protein kinases and phosphatases, leading to changes in cellular responses. MAFP's unique ability to influence lipid composition on cellular membranes can significantly impact receptor activation and downstream signaling events. | ||||||
PD 174265 | 216163-53-0 | sc-204170 | 1 mg | $160.00 | 4 | |
PD 174265 is a potent modulator of signal transduction, specifically influencing the phosphorylation state of target proteins. It selectively inhibits certain kinases, thereby altering the cascade of intracellular signaling pathways. This compound exhibits unique binding affinity, which stabilizes specific conformations of proteins, affecting their activity and interactions. Its kinetic profile reveals rapid onset and sustained effects, making it a critical tool for dissecting complex cellular signaling networks. | ||||||
p38 MAP Kinase Inhibitor | 219138-24-6 | sc-204157 sc-204157A | 500 µg 5 mg | $160.00 $1168.00 | 1 | |
The p38 MAP Kinase Inhibitor is a selective antagonist that disrupts the phosphorylation of MAPK pathways, crucial for cellular responses to stress. By binding to the ATP-binding site of p38 MAPK, it alters the enzyme's conformation, inhibiting its catalytic activity. This compound exhibits unique interaction dynamics, leading to a decrease in downstream signaling events. Its specificity allows for targeted modulation of cellular processes, providing insights into the intricacies of signal transduction mechanisms. | ||||||
PIK-75, free base | 372196-67-3 | sc-394297 | 5 mg | $81.00 | 1 | |
PIK-75, free base, is a potent inhibitor that selectively targets specific kinases involved in signal transduction pathways. By engaging with the ATP-binding pocket, it induces conformational changes that hinder kinase activity, effectively modulating cellular signaling cascades. Its unique binding affinity and kinetic profile allow for precise regulation of phosphorylation events, influencing various cellular responses. This compound's distinct interaction patterns contribute to a deeper understanding of the molecular mechanisms governing cellular communication. | ||||||
Exo1 | 461681-88-9 | sc-200752 sc-200752A | 10 mg 50 mg | $82.00 $291.00 | 4 | |
Exo1 is a critical enzyme involved in the regulation of signal transduction, particularly in the context of DNA repair and cellular response to stress. It exhibits unique interactions with DNA substrates, facilitating the processing of DNA ends through its exonuclease activity. This specificity enhances its role in modulating signaling pathways related to genomic stability. The enzyme's kinetic properties allow for rapid response to DNA damage, influencing downstream signaling events and cellular fate decisions. | ||||||
L-744,832 Dihydrochloride | 1177806-11-9 | sc-221800 sc-221800A | 5 mg 25 mg | $550.00 $1796.00 | 2 | |
L-744,832 Dihydrochloride is a potent modulator of signal transduction pathways, particularly influencing G-protein coupled receptor (GPCR) signaling. Its unique ability to selectively inhibit specific kinases alters phosphorylation states of target proteins, thereby impacting cellular communication and response mechanisms. The compound exhibits distinct binding affinities, which can lead to differential activation of downstream effectors, ultimately shaping cellular behavior and functional outcomes. | ||||||
Theobromine | 83-67-0 | sc-203296 sc-203296A | 25 g 100 g | $41.00 $87.00 | ||
Theobromine acts as a signaling molecule by modulating intracellular calcium levels and influencing cyclic nucleotide pathways. Its interaction with adenosine receptors can lead to altered neurotransmitter release, affecting synaptic plasticity. Additionally, theobromine's role in inhibiting phosphodiesterase enzymes enhances cyclic AMP concentrations, further amplifying signal transduction cascades. This multifaceted behavior contributes to its diverse physiological effects at the cellular level. | ||||||
4-Aminopyridine | 504-24-5 | sc-202421 sc-202421B sc-202421A | 25 g 1 kg 100 g | $37.00 $1132.00 $120.00 | 3 | |
4-Aminopyridine functions as a potent modulator of ion channel activity, particularly influencing potassium channels. By blocking these channels, it enhances neuronal excitability and alters action potential propagation. This compound also interacts with various neurotransmitter systems, potentially affecting synaptic transmission dynamics. Its unique ability to alter membrane potential and influence ion flux contributes to its role in signal transduction pathways, impacting cellular communication. | ||||||
Clonidine hydrochloride | 4205-91-8 | sc-203002 | 1 g | $367.00 | 12 | |
Clonidine hydrochloride acts as an agonist at alpha-2 adrenergic receptors, leading to a decrease in neurotransmitter release. This interaction initiates a cascade of intracellular signaling, primarily involving inhibition of adenylate cyclase and reduction of cyclic AMP levels. The compound's affinity for these receptors modulates calcium ion influx, influencing smooth muscle contraction and neurotransmitter release, thereby playing a critical role in various signal transduction pathways. | ||||||