Theobromine (CAS 83-67-0)
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Theobromine is extensively employed in food science research, particularly in studies focusing on its effects on flavor and health properties of cocoa and chocolate products. Its role in enhancing bitterness while contributing to the characteristic flavor of chocolate makes it a subject of interest in sensory evaluation studies. In agricultural research, theobromine is studied for its natural occurrence in cocoa plants and the factors affecting its concentration within different cocoa varieties. Environmental studies also utilize theobromine to understand how growing conditions and processing methods impact the levels of bioactive compounds in cocoa. Furthermore, theobromine is utilized in nutritional research to explore its influence on fatigue and alertness, providing insights into how bioactive compounds can affect human physiological responses.
Theobromine (CAS 83-67-0) References
- Theobromine up-regulates cerebral brain-derived neurotrophic factor and facilitates motor learning in mice. | Yoneda, M., et al. 2017. J Nutr Biochem. 39: 110-116. PMID: 27833051
- Chronic administration of theobromine inhibits mTOR signal in rats. | Sugimoto, N., et al. 2019. Basic Clin Pharmacol Toxicol. 124: 575-581. PMID: 30451374
- Theobromine alleviates diet-induced obesity in mice via phosphodiesterase-4 inhibition. | Jang, MH., et al. 2020. Eur J Nutr. 59: 3503-3516. PMID: 31965293
- Exploration of the theobromine-water dimer: comparison with DNA microhydration. | Usabiaga, I., et al. 2020. Phys Chem Chem Phys. 22: 15759-15768. PMID: 32627788
- 3-Methylxanthine production through biodegradation of theobromine by Aspergillus sydowii PT-2. | Zhou, B., et al. 2020. BMC Microbiol. 20: 269. PMID: 32854634
- Efficacy of theobromine in preventing intestinal CaCo-2 cell damage induced by oxysterols. | Iaia, N., et al. 2020. Arch Biochem Biophys. 694: 108591. PMID: 32961113
- The effect of theobromine on the in vitro de- and remineralization of enamel carious lesions. | Thorn, AK., et al. 2020. J Dent. 103S: 100013. PMID: 34059300
- Neuroprotective effects of theobromine in transient global cerebral ischemia-reperfusion rat model. | Bhat, JA., et al. 2021. Biochem Biophys Res Commun. 571: 74-80. PMID: 34303966
- Theobromine enhances the conversion of white adipocytes into beige adipocytes in a PPARγ activation-dependent manner. | Tanaka, E., et al. 2022. J Nutr Biochem. 100: 108898. PMID: 34748921
- Effects of long-term treatment with dietary theobromine on rat skeletal muscles. | Tanaka, S., et al. 2022. Mol Biol Rep. 49: 3965-3973. PMID: 35226259
- Neuroprotective Effects of Theobromine in permanent bilateral common carotid artery occlusion rat model of cerebral hypoperfusion. | Bhat, JA. and Kumar, M. 2022. Metab Brain Dis. 37: 1787-1801. PMID: 35587851
- Effect of theobromine on dissolution of uric acid kidney stones. | Julià, F., et al. 2022. World J Urol. 40: 2105-2111. PMID: 35689678
- Association between dietary theobromine with depression: a population-based study. | Li, XY., et al. 2022. BMC Psychiatry. 22: 769. PMID: 36474233
- Determination of caffeine, paraxanthine, theophylline and theobromine in premature infants by HILIC-MS/MS. | Wen, SY., et al. 2022. Bioanalysis. 14: 1497-1508. PMID: 36825935
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Theobromine, 25 g | sc-203296 | 25 g | $41.00 | |||
Theobromine, 100 g | sc-203296A | 100 g | $87.00 |