Molecular structure of p38 MAP Kinase Inhibitor, CAS Number: 219138-24-6
p38 MAP Kinase Inhibitor (CAS 219138-24-6)
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Alternate Names:
2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one
Application:
p38 MAP Kinase Inhibitor is a potent p38 MAP kinase inhibitor
CAS Number:
219138-24-6
Purity:
>95%
Molecular Weight:
365.8
Molecular Formula:
C20H13ClFN3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A p38 MAP Kinase Inhibitor is a compound that selectively inhibits the activity of p38 mitogen-activated protein kinases, which are a class of enzymes involved in cellular responses to stress and inflammatory cytokines. These inhibitors are tools for dissecting the signaling pathways mediated by p38 MAPK, which include the regulation of proinflammatory cytokine production, apoptosis, and cell differentiation. Researchers employ p38 MAP Kinase Inhibitors to study their role in modulating the inflammatory response and to understand the molecular basis of diseases where p38 MAPK is implicated. By inhibiting p38 MAPK activity, researchers can explore the kinase′s contributions to cellular processes and its interactions with other signaling molecules.
p38 MAP Kinase Inhibitor (CAS 219138-24-6) References
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- Human neutrophils are targets to paracoccin, a lectin expressed by Paracoccidioides brasiliensis. | Ricci-Azevedo, R., et al. 2018. Inflamm Res. 67: 31-41. PMID: 29018875
- Effect of baicalin on GLUT4 expression and glucose uptake in myotubes of rats. | Fang, P., et al. 2018. Life Sci. 196: 156-161. PMID: 29459024
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Inhibitor of:
EG216818, p38 alpha, and Ser/Thr Protein Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p38 MAP Kinase Inhibitor, 500 µg | sc-204157 | 500 µg | $163.00 | |||
p38 MAP Kinase Inhibitor, 5 mg | sc-204157A | 5 mg | $1191.00 |