SID-1 Inhibitors
SID-1 Inhibitors belong to a distinct chemical class characterized by their capacity to modulate the activity of SID-1 (Systemic RNA Interference Deficient-1) proteins within biological systems. SID-1 proteins are integral components of the RNA interference (RNAi) pathway, a conserved mechanism for post-transcriptional gene silencing. These inhibitors specifically target SID-1, a transmembrane protein responsible for the systemic spread of small RNA molecules, including small interfering RNAs (siRNAs), across cell membranes. By hindering the function of SID-1, these inhibitors interrupt the transmembrane transport of RNA molecules, thereby influencing the intricate regulatory network of gene expression.
SID-1 Inhibitors involves the interference with the systemic distribution of RNA signals, which play a pivotal role in orchestrating gene silencing events. These inhibitors typically interact with specific binding sites on SID-1, impeding its ability to facilitate the uptake of small RNAs from the extracellular environment. As a consequence, the spatial propagation of RNAi signals is disrupted, leading to altered patterns of gene expression within the organism. The development and study of SID-1 Inhibitors contribute to advancing our understanding of RNA interference pathways and their broader implications in biological processes.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that may reduce SIDT1-related endocytosis by altering membrane trafficking. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor that could alter cellular processes involving SIDT1 through modulation of autophagy. | ||||||
Autophagy Inhibitor, 3-MA | 5142-23-4 | sc-205596 sc-205596A | 50 mg 500 mg | $65.00 $261.00 | 113 | |
An autophagy inhibitor that can affect the degradation pathways which could be indirectly related to SIDT1. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
A GTPase inhibitor for dynamin that can impede endocytosis, potentially affecting SIDT1-associated trafficking. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A tyrosine kinase inhibitor that may modulate signal transduction pathways influencing SIDT1 function. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
Alters membrane trafficking and endocytosis which could indirectly affect SIDT1's role in cellular transport. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
An ionophore that disrupts endosomal pH and could influence SIDT1 related transport mechanisms. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $98.00 $255.00 $765.00 $1457.00 | 280 | |
A V-ATPase inhibitor, affecting vesicular acidification which could indirectly affect SIDT1 function. | ||||||
FCM Lysing solution (1x) | sc-3621 | 150 ml | $62.00 | 8 | ||
Ammonium chloride can raise endosomal pH, potentially influencing SIDT1 activity by altering its environment. | ||||||
U 18666A | 3039-71-2 | sc-203306 sc-203306A | 10 mg 50 mg | $143.00 $510.00 | 2 | |
It influences cholesterol trafficking and could thus affect the membrane dynamics related to SIDT1. | ||||||