Date published: 2025-11-1

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Sialin Inhibitors

Sialin inhibitors belong to a specific category of chemical compounds that play a significant role in the modulation of sialin, a transmembrane protein involved in the transport of sialic acid, a critical component of cell surface glycoproteins and glycolipids. Sialic acid serves several essential functions in biological systems, including cell adhesion, signal transduction, and the regulation of immune responses. The inhibition of sialin is primarily associated with its impact on the cellular transport of sialic acid. Sialin inhibitors are designed to interfere with the activity of sialin, thus influencing the cellular levels and distribution of sialic acid.

These inhibitors typically function by binding to sialin and disrupting its ability to facilitate the transport of sialic acid across cellular membranes. As a result, they can lead to alterations in sialic acid metabolism and distribution within the cell. The modulation of sialic acid levels can have far-reaching consequences, as it can impact various cellular processes and interactions. Sialin inhibitors have garnered attention in scientific research due to their potential to shed light on the fundamental mechanisms of sialic acid transport and metabolism within cells. Understanding the intricacies of sialin inhibition can provide valuable insights into the broader field of glycobiology, as sialic acid is a crucial component of glycosylation processes that influence cell function and communication. Researchers continue to explore the mechanisms and potential applications of sialin inhibitors in various biological contexts, making them a subject of ongoing investigation in the scientific community.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

AM 80

94497-51-5sc-203816
sc-203816A
10 mg
50 mg
$155.00
$620.00
1
(1)

AM 80, a synthetic retinoid, can modulate the expression of sialin indirectly through its action on gene transcription.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zinc Pyrithione can alter transmembrane transport and may affect sialin's transporter function.

Probenecid

57-66-9sc-202773
sc-202773A
sc-202773B
sc-202773C
1 g
5 g
25 g
100 g
$27.00
$38.00
$98.00
$272.00
28
(2)

Probenecid inhibits various anion transporters and may influence the anion transport activity of sialin.

5-(N-Ethyl-N-isopropyl)-Amiloride

1154-25-2sc-202458
5 mg
$102.00
20
(1)

EIPA, an inhibitor of Na+/H+ exchange, can indirectly affect the cellular pH and thus sialin's transport efficiency.

Bafilomycin A1

88899-55-2sc-201550
sc-201550A
sc-201550B
sc-201550C
100 µg
1 mg
5 mg
10 mg
$96.00
$250.00
$750.00
$1428.00
280
(6)

Bafilomycin A1 specifically inhibits V-ATPase, potentially altering vesicular pH and impacting sialin's role in vesicular acidification.

Tenofovir

147127-20-6sc-204335
sc-204335A
10 mg
50 mg
$154.00
$633.00
11
(1)

Tenofovir, an antiviral drug, can inhibit nucleotide/nucleoside transporters, potentially affecting sialin's function.

Suramin sodium

129-46-4sc-507209
sc-507209F
sc-507209A
sc-507209B
sc-507209C
sc-507209D
sc-507209E
50 mg
100 mg
250 mg
1 g
10 g
25 g
50 g
$149.00
$210.00
$714.00
$2550.00
$10750.00
$21410.00
$40290.00
5
(1)

Suramin can inhibit various purinergic receptors and transporters, which may indirectly alter sialin's function.

Chloroquine

54-05-7sc-507304
250 mg
$68.00
2
(0)

Chloroquine raises endosomal pH, which may influence sialin's role in pH-dependent transport.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Genistein, a tyrosine kinase inhibitor, can modulate various signaling pathways and may indirectly affect sialin's function.

Verapamil

52-53-9sc-507373
1 g
$367.00
(0)

Verapamil, a calcium channel blocker, can influence ion homeostasis and indirectly affect sialin's transport activity.