SHROOM4 activators are chemicals that target and increase the activity of SHROOM4, a protein that plays a role in cellular structure and regulation. SHROOM4 belongs to the Shroom family of proteins, which are known to interact with components of the cell's cytoskeleton, particularly actin filaments. These interactions are important for various cellular processes, including cell shape, division, and differentiation. SHROOM4 has been identified to have a role in the way that cells and tissues shape themselves, which is a critical aspect of normal development. Activators of SHROOM4 are molecules that either enhance the protein's natural activity or increase its expression levels within the cell.
The development of SHROOM4 activators typically involves the identification and synthesis of compounds that can either bind to the SHROOM4 protein and stabilize it in an active conformation or affect the signaling pathways that regulate its activity and expression. The molecular design of these activators is informed by a detailed understanding of the structure and function of SHROOM4, including the domains that are critical for its interaction with actin and other proteins involved in cytoskeletal dynamics. Structural biology techniques such as X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy can provide insights into the three-dimensional arrangement of SHROOM4, which is crucial for the rational design of molecules that can modulate its activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid may stimulate the transcriptional activities of certain genes. It could possibly upregulate SHROOM4 by promoting the assembly of transcriptional machinery. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
β-Estradiol binds to its specific receptors to initiate gene transcription. It might hypothetically upregulate SHROOM4 expression through estrogen receptor-mediated pathways. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine could potentially enhance SHROOM4 expression by triggering cellular signaling pathways related to stress responses, leading to increased transcriptional activity. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Cholecalciferol could theoretically induce SHROOM4 expression by interacting with vitamin D receptors and stimulating transcriptional activities related to cellular differentiation. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin could potentially stimulate SHROOM4 gene transcription as part of its broader role in cellular metabolic processes. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine could indirectly stimulate SHROOM4 expression by enhancing cellular stress responses and energy metabolism, leading to increased gene transcription. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol may increase SHROOM4 expression indirectly by enhancing transcriptional activity related to longevity and stress resistance. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin could potentially stimulate SHROOM4 expression indirectly by enhancing the transcription of genes related to inflammation and stress responses. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
L-Ascorbic acid could potentially stimulate SHROOM4 expression indirectly by enhancing the transcriptional activity of genes related to cellular repair and recovery. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
Nicotinamide could theoretically stimulate SHROOM4 expression indirectly through its role in cellular metabolism and redox reactions, leading to increased transcriptional activity. | ||||||