Date published: 2025-11-18

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Shank 3 Antibodies

Santa Cruz Biotechnology delivers a wide array of Shank 3 monoclonal antibodies for research in neuroscience and synaptic function. Shank 3 Antibodies are available for various applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Shank 3 is a critical scaffolding protein located at the postsynaptic density of excitatory synapses, playing a vital role in synaptic signaling and plasticity. It is essential for the proper formation and maintenance of synapses, and its dysfunction has been implicated in neurodevelopmental disorders such as autism spectrum disorder and schizophrenia. Understanding the role of Shank 3 in synaptic function is crucial for advancing our knowledge of these complex conditions. Researchers can explore molecular mechanisms underlying synaptic transmission and investigate implications in neurological diseases. Shank 3 monoclonal antibodies enable detailed examination of protein interactions and signaling pathways in neural networks. Advanced research techniques supported by Shank 3 monoclonal antibodies help uncover new therapeutic targets for neurodevelopmental disorders. Santa Cruz Biotechnology monoclonal antibodies for Shank 3 continue to support breakthrough discoveries in neuroscience research worldwide.

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Shank 3 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Shank 1/2/3 Antibody (G-12)

sc-393963mouse IgG2a κ2124-2153 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(2)

Shank 3 Antibody (C-4)

sc-377088mouse IgG1 κ1431-1590 (h)WB, IP, IF, ELISAm, r, h
8
(5)

Shank 3 Antibody (E-1)

sc-377470mouse IgG2a κ1431-1590 (h)WB, IP, IF, ELISAm, r, h
3
(4)

Shank 3 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Shank 3 CRISPR/Cas9 KO Plasmid (m)

sc-425500mGene KnockoutGFP0
(0)

Shank 3 HDR Plasmid (m)

sc-425500-HDRmHomology Directed RepairPuromycin0
(0)

Shank 3 Double Nickase Plasmid (m)

sc-425500-NICmGene KnockoutPuromycin0
(0)

Shank 3 Double Nickase Plasmid (m2)

sc-425500-NIC-2mGene KnockoutPuromycin0
(0)

Shank 3 CRISPR Activation Products

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Shank 3 CRISPR Activation Plasmid (m)

sc-425500-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Shank 3 CRISPR Activation Plasmid (m2)

sc-425500-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Shank 3 Lentiviral Activation Particles (m)

sc-425500-LACmGene ActivationPuro, Blast, Hygro0
(0)

Shank 3 Lentiviral Activation Particles (m2)

sc-425500-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Shank 3 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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Shank 3 siRNA (h)

sc-42200hGene SilencingN/A0
(0)

Shank 3 shRNA Plasmid (h)

sc-42200-SHhGene SilencingPuromycin0
(0)

Shank 3 shRNA (h) Lentiviral Particles

sc-42200-VhGene SilencingPuromycin0
(0)

Shank 3 siRNA (m)

sc-42201mGene SilencingN/A0
(0)

Shank 3 shRNA Plasmid (m)

sc-42201-SHmGene SilencingPuromycin0
(0)

Shank 3 shRNA (m) Lentiviral Particles

sc-42201-VmGene SilencingPuromycin0
(0)

Shank 3 siRNA (r)

sc-270274rGene SilencingN/A
1
(0)

Shank 3 shRNA Plasmid (r)

sc-270274-SHrGene SilencingPuromycin
1
(0)

Shank 3 shRNA (r) Lentiviral Particles

sc-270274-VrGene SilencingPuromycin
1
(0)