Date published: 2025-11-18

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Shank 2 Antibodies

Santa Cruz Biotechnology features a diverse variety of Shank 2 monoclonal antibodies for research in neuroscience and cellular biology. Shank 2 Antibodies are available for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Shank 2 is a scaffolding protein that plays a vital role in the organization of synaptic structures and the regulation of synaptic signaling. Shank 2 maintains proper functioning of excitatory synapses and has been linked to various neurodevelopmental disorders, making it a significant target for research in understanding synaptic dysfunction. The study of Shank 2 continues to reveal important insights into molecular mechanisms underlying cognitive processes and neuropsychiatric conditions. Understanding Shank 2's role in synaptic organization has opened new avenues for investigating neural circuit development and plasticity. Research focusing on Shank 2 has enhanced our knowledge of synaptic protein interactions and their impact on neuronal communication. Ongoing investigations of Shank 2 contribute to developing therapeutic strategies for neurodevelopmental disorders. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of synaptic biology and its implications in neurological health and disease.

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Shank 2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Shank 1/2/3 Antibody (G-12)

sc-393963mouse IgG2a κ2124-2153 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(2)

Shank 2 Antibody (A-11)

sc-271834mouse IgG1 κ996-1110 (h)WB, IP, IF, ELISAm, r, h
2
(5)

Shank 2 Antibody (B-4)

sc-365121mouse IgG2b κ996-1110 (h)WB, IP, IF, ELISAm, r, h
1
(2)

Shank 2 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Shank 2 CRISPR/Cas9 KO Plasmid (h)

sc-403143hGene KnockoutGFP0
(0)

Shank 2 HDR Plasmid (h)

sc-403143-HDRhHomology Directed RepairPuromycin0
(0)

Shank 2 Double Nickase Plasmid (h)

sc-403143-NIChGene KnockoutPuromycin0
(0)

Shank 2 Double Nickase Plasmid (h2)

sc-403143-NIC-2hGene KnockoutPuromycin0
(0)

Shank2 CRISPR/Cas9 KO Plasmid (m)

sc-431686mGene KnockoutGFP0
(0)

Shank2 HDR Plasmid (m)

sc-431686-HDRmHomology Directed RepairPuromycin0
(0)

Shank2 Double Nickase Plasmid (m)

sc-431686-NICmGene KnockoutPuromycin0
(0)

Shank2 Double Nickase Plasmid (m2)

sc-431686-NIC-2mGene KnockoutPuromycin0
(0)

Shank 2 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Shank 2 CRISPR Activation Plasmid (h)

sc-403143-ACThGene ActivationPuro, Blast, Hygro0
(0)

Shank 2 CRISPR Activation Plasmid (h2)

sc-403143-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Shank 2 Lentiviral Activation Particles (h)

sc-403143-LAChGene ActivationPuro, Blast, Hygro0
(0)

Shank 2 Lentiviral Activation Particles (h2)

sc-403143-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Shank2 CRISPR Activation Plasmid (m)

sc-431686-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Shank2 CRISPR Activation Plasmid (m2)

sc-431686-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Shank2 Lentiviral Activation Particles (m)

sc-431686-LACmGene ActivationPuro, Blast, Hygro0
(0)

Shank2 Lentiviral Activation Particles (m2)

sc-431686-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Shank 2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Shank 2 siRNA (h)

sc-42198hGene SilencingN/A0
(0)

Shank 2 shRNA Plasmid (h)

sc-42198-SHhGene SilencingPuromycin0
(0)

Shank 2 shRNA (h) Lentiviral Particles

sc-42198-VhGene SilencingPuromycin0
(0)

Shank 2 siRNA (m)

sc-42199mGene SilencingN/A0
(0)

Shank 2 shRNA Plasmid (m)

sc-42199-SHmGene SilencingPuromycin0
(0)

Shank 2 shRNA (m) Lentiviral Particles

sc-42199-VmGene SilencingPuromycin0
(0)