SerpinB12 Inhibitors
SerpinB12 inhibitors target and inhibit the activity of SerpinB12, a member of the serine protease inhibitor (serpin) superfamily. Serpins are known for their role in regulating proteases, enzymes that catalyze the breakdown of proteins. SerpinB12, in particular, is involved in inhibiting specific serine proteases. The structure of SerpinB12, like other serpins, is characterized by a conserved tertiary structure with a reactive center loop (RCL) that acts as a bait for target proteases. Upon interaction with a protease, the RCL undergoes a conformational change, leading to the inhibition of the protease's enzymatic activity. The functionality of SerpinB12 is integral to various physiological processes, including inflammation and coagulation. Inhibitors of SerpinB12 are designed to selectively interact with the protein, aiming to modulate its protease-inhibiting activity by targeting the RCL or other key structural elements essential for its function.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid, has been shown to modulate various cellular pathways, including those involved in inflammation and oxidative stress, potentially influencing SerpinB12 expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin gallate (EGCG), a major component of green tea, is known for its antioxidant properties. It might affect SerpinB12 expression by modulating cellular antioxidant responses. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, found in grapes and berries, is involved in the modulation of various signaling pathways. Its impact on SerpinB12 expression could be through pathways related to cellular stress and aging. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, from turmeric, is known for its anti-inflammatory properties. It could influence SerpinB12 expression by modulating inflammatory pathways and the activity of transcription factors. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, a soy isoflavone, has been shown to affect various cellular signaling pathways, including those related to hormone activity, which might indirectly influence SerpinB12 expression. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $57.00 $93.00 $240.00 $713.00 | 8 | |
Ellagic acid, found in fruits like pomegranates, is an antioxidant and has been shown to modulate various pathways involved in inflammation and oxidative stress, potentially affecting SerpinB12 expression. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $38.00 $60.00 $143.00 $306.00 $1012.00 | 5 | |
Indole-3-carbinol, found in cruciferous vegetables, is known to modulate estrogen metabolism and may affect SerpinB12 expression through pathways involved in hormone regulation. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $143.00 $571.00 $6125.00 | 4 | |
Lycopene, a carotenoid found in tomatoes, may influence SerpinB12 expression by affecting oxidative stress pathways and cellular signaling related to inflammation. | ||||||
Caffeic Acid | 331-39-5 | sc-200499 sc-200499A | 1 g 5 g | $31.00 $61.00 | 1 | |
Caffeic acid, a phenolic compound found in various plants, has antioxidant properties and could potentially influence SerpinB12 expression by modulating cellular responses to oxidative stress. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $32.00 $210.00 $720.00 $1128.00 $2302.00 $3066.00 $5106.00 | 22 | |
Apigenin, a flavone found in many plants, is known to affect several signaling pathways involved in inflammation and might indirectly influence the expression of SerpinB12. | ||||||