SEMA3C Inhibitors
SEMA3C Inhibitors consist of a range of compounds that indirectly decrease the activity of SEMA3C, a protein known for its role in neuronal guidance and development. These inhibitors function by impacting the signaling pathways and cellular processes SEMA3C is involved in. The primary mechanism through which these inhibitors work is by altering signaling pathways related to neuronal growth and development. Compounds such as Rapamycin, LY294002, and PD98059 target key signaling pathways like mTOR, PI3K, and MAPK, respectively. By modulating these pathways, they can indirectly influence the activity of SEMA3C in the context of neuronal development. Inhibitors like Cyclopamine and Wnt pathway inhibitors (e.g., IWP-2) disrupt other critical signaling pathways, such as Hedgehog and Wnt, which could intersect with SEMA3C-related processes.
Additionally, inhibitors of NF-kappaB signaling and Notch signaling, such as BAY 11-7082 and DAPT, can affect cellular processes where SEMA3C is involved. The FGF receptor inhibitor SU5402 and the ROCK inhibitor Y-27632 offer other examples of compounds that indirectly reduce SEMA3C activity by influencing related signaling pathways. Even compounds like SP600125, which is primarily a JNK inhibitor, might lead to indirect SEMA3C inhibition under certain cellular contexts.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, could disrupt pathways involved in neuronal growth and development, potentially reducing SEMA3C activity. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $94.00 $208.00 | 19 | |
Inhibits the Hedgehog signaling pathway, which may intersect with pathways involving SEMA3C. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor, potentially impacting signaling pathways related to neuronal development and SEMA3C activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
A MEK inhibitor, could disrupt MAPK signaling pathway, potentially affecting SEMA3C activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
An inhibitor of p38 MAPK, potentially influencing pathways related to SEMA3C. | ||||||
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $96.00 $292.00 | 27 | |
Inhibits Wnt signaling, which might have an impact on SEMA3C activity in neuronal processes. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
Inhibits NF-kappaB signaling, potentially affecting pathways related to SEMA3C. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $40.00 $120.00 $480.00 $2141.00 | 47 | |
A Notch signaling inhibitor, potentially impacting pathways involving SEMA3C. | ||||||
SU 5402 | 215543-92-3 | sc-204308 sc-204308A | 1 mg 5 mg | $63.00 $98.00 | 36 | |
A FGF receptor inhibitor, could indirectly affect SEMA3C activity by impacting related signaling pathways. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor, which might influence pathways related to SEMA3C in neuronal development. | ||||||