'SECp43 Inhibitors' refers to a class of compounds that are not necessarily direct antagonists of the SECp43 protein but can modulate the protein's activity through indirect mechanisms. These inhibitors function by intervening in cellular signaling pathways, protein synthesis, and post-translational modifications that SECp43 may be a part of or influence. For example, inhibitors of key kinases such as phosphoinositide 3-kinases (PI3K) and mammalian target of rapamycin (mTOR) can disrupt downstream signaling pathways that may govern SECp43's regulatory functions, thereby modulating its activity.
These chemicals can also influence the transcriptional and translational machinery of the cell, such as histone deacetylases and DNA methyltransferases, which in turn can affect the expression and function of SECp43. Glycolysis inhibitors and agents that interfere with glycosylation processes can alter cellular metabolism and protein processing, respectively, which may also impact SECp43's role in the cell. By affecting these biological processes and signaling cascades, the chemicals listed can indirectly inhibit SECp43's function within the cell. Each of these compounds has unique mechanisms of action, and their effects on SECp43 depend on the context of the protein's expression and the cell's physiological state.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A phosphoinositide 3-kinase inhibitor that can disrupt downstream signaling affecting SECp43 activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Another PI3K inhibitor that can alter the phosphorylation state of proteins potentially interacting with SECp43. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can modify the translation process in which SECp43 may be implicated. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Inhibits eukaryotic protein synthesis which could indirectly affect SECp43 function. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor that can change transcription patterns of genes encoding proteins interacting with SECp43. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, potentially altering the expression of SECp43 or its interacting partners. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAP kinase inhibitor, could alter stress responses that modulate SECp43's role. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, which might affect signaling pathways involving SECp43. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
A MEK inhibitor that could indirectly influence SECp43's function through the MAPK pathway. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
A glycolysis inhibitor that may alter the cellular energy state, potentially affecting SECp43. | ||||||