The class of chemicals known as SEC22B Inhibitors encompasses compounds that could potentially interfere with the function of SEC22B by impacting related cellular processes, particularly those involved in vesicle trafficking and cytoskeletal dynamics. These chemicals do not inhibit SEC22B directly but affect various biochemical pathways and cellular processes, creating conditions that may hinder SEC22B's role in protein transport.
Compounds like Brefeldin A, Monensin, and Golgicide A target Golgi apparatus function, which is closely related to SEC22B's role in vesicle transport. By disrupting Golgi structure and function, these chemicals can indirectly inhibit the vesicle trafficking processes mediated by SEC22B. Similarly, agents that affect cytoskeletal elements, such as Nocodazole, Colchicine, Cytochalasin D, and Latrunculin A, could inhibit SEC22B by disrupting the cytoskeletal framework essential for vesicle movement. Other inhibitors, such as Tunicamycin and Dynasore, target specific aspects of vesicle formation and processing, potentially affecting SEC22B-mediated transport. Compounds like Genistein and Wortmannin, known for their roles in modulating signaling pathways, could indirectly affect SEC22B's function in vesicle trafficking by altering cellular signaling relevant to this process.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Disrupts the structure of the Golgi apparatus, potentially inhibiting SEC22B's role in vesicle trafficking between the ER and Golgi. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
A carboxylic ionophore that disrupts Golgi function, potentially inhibiting SEC22B-mediated vesicle transport. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Disrupts microtubule dynamics, potentially affecting vesicle transport processes in which SEC22B is involved. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Another microtubule-disrupting agent, potentially inhibiting SEC22B's role in vesicle trafficking. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Inhibits actin polymerization, potentially affecting the cytoskeletal dynamics crucial for SEC22B-mediated vesicle transport. | ||||||
Golgicide A | 1005036-73-6 | sc-215103 sc-215103A | 5 mg 25 mg | $191.00 $683.00 | 11 | |
Specifically disrupts Golgi function, potentially inhibiting SEC22B's role in vesicle trafficking. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Inhibits N-linked glycosylation, affecting protein folding and potentially impacting SEC22B's function in vesicle transport. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Inhibits dynamin, potentially affecting the vesicle scission process in which SEC22B is involved. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A tyrosine kinase inhibitor, potentially modulating signaling pathways that influence SEC22B's vesicle trafficking function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A PI3K inhibitor, could indirectly affect vesicle trafficking processes involving SEC22B. | ||||||