Sam 68 Activators refer to a class of chemical compounds that exert their influence on a cellular protein known as Sam 68, or Src-associated substrate during mitosis of 68 kDa. Sam 68 is a member of the signal transduction and activation of RNA (STAR) family of RNA-binding proteins, which play pivotal roles in post-transcriptional gene regulation. These activators are designed to modulate the activity of Sam 68 by binding to it or altering its conformation, thereby influencing its downstream cellular functions. Sam 68 itself is a multifunctional protein that is primarily associated with the regulation of mRNA splicing, transport, and stability, making it a crucial player in the intricate network of cellular processes that control gene expression.
The chemical class of Sam 68 activators encompasses a diverse range of compounds, each with distinct mechanisms of action. Some activators may enhance the binding of Sam 68 to specific RNA molecules, promoting alternative splicing events or stabilizing mRNA transcripts. Others may target post-translational modifications of Sam 68, such as phosphorylation, which can impact its interactions with other proteins and RNA.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a polyphenolic compound found in grapes and red wine, has been reported to influence various signaling pathways associated with cellular growth and survival, potentially leading to the modulation of Sam 68 expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Found in cruciferous vegetables, sulforaphane is a compound that has been linked to the activation of antioxidant response elements and may influence the expression of Sam 68 through its effects on cellular oxidative stress responses. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin is a bioactive compound from turmeric with anti-inflammatory and antioxidant properties. It can modulate various signaling pathways, potentially affecting Sam 68 expression levels and its associated cellular functions. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid present in many fruits and vegetables, has been associated with anti-inflammatory and antioxidant activities. It may impact Sam 68 expression through its influence on cellular signaling pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, a major catechin in green tea, has been shown to exert various biological effects, including modulation of signaling pathways. These effects may potentially lead to changes in Sam 68 expression levels. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate, a short-chain fatty acid, has histone deacetylase inhibitory activity, potentially leading to changes in gene expression, including that of Sam 68. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a metabolite of vitamin A, is involved in gene regulation and cellular differentiation. It may modulate Sam 68 expression as part of its role in regulating gene transcription. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin is a compound found in the Coleus forskohlii plant, known to activate adenylate cyclase and increase cAMP levels. Through these effects, forskolin may influence Sam 68 expression and associated cellular activities. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc is an essential mineral with various biological roles, including gene expression regulation. Zinc sulfate supplementation could potentially influence Sam 68 expression through its effects on cellular zinc levels. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
As a reactive oxygen species, hydrogen peroxide can influence cellular signaling pathways and stress responses. These effects may potentially lead to changes in Sam 68 expression. | ||||||