Sall2 Activators
Sall2 activators belong to a specific chemical class that revolves around the modulation of the Sall2 gene, a member of the Spalt-like family of transcription factors. The term "Sall2" is found in the Sal-like (Sall) gene family, which encodes zinc finger transcription factors crucial for embryonic development and cellular differentiation. Sall2, in particular, plays a pivotal role in various biological processes, including the regulation of cell cycle progression, apoptosis, and embryonic development. The chemical class of Sall2 activators encompasses a diverse range of compounds specifically designed to enhance the transcriptional activity of the Sall2 gene.
At the molecular level, Sall2 activators typically interact with the regulatory regions of the Sall2 gene, such as its promoter or enhancer sequences. These compounds may exert their effects through various mechanisms, including direct binding to specific sites on the DNA or through interactions with other proteins involved in the transcriptional machinery. By promoting the activation of the Sall2 gene, these compounds have the ability to influence downstream cellular processes governed by Sall2, thereby contributing to the modulation of fundamental biological pathways. Understanding the intricacies of Sall2 activators provides valuable insights into the molecular mechanisms underlying gene expression regulation and opens avenues for further research aimed at elucidating their specific roles in cellular and developmental processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid is a metabolite of vitamin A. It activates retinoic acid receptor (RAR) and retinoid X receptor (RXR), which then bind to retinoic acid response elements (RAREs) in the DNA to modulate gene expression. This can enhance the function of Sall2, as it is also a DNA-binding transcription factor that regulates gene expression. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Estradiol is an estrogen steroid hormone. It binds to and activates the estrogen receptor, which then modulates gene expression by binding to estrogen response elements (EREs) in the DNA. Given that Sall2 is a transcription factor, estradiol can enhance its functional activity by influencing the overall transcriptional machinery of the cell. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone is a synthetic glucocorticoid that binds to and activates the glucocorticoid receptor. It enhances the function of Sall2 by indirectly influencing transcriptional regulation within the cell. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin directly activates adenylate cyclase, increasing the levels of cyclic AMP (cAMP) in cells. cAMP is a second messenger that regulates numerous cellular processes, potentially enhancing Sall2 function by influencing the downstream signaling pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is a polyphenol compound found in green tea. It is known to activate the 67-kDa laminin receptor and modulate downstream signaling pathways, potentially enhancing the functional activation of Sall2. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a plant compound acting as an activator of SIRT1, a NAD+-dependent deacetylase. It is involved in the regulation of energy metabolism and mitochondrial biogenesis, potentially enhancing the function of Sall2. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane is a compound found in broccoli and other cruciferous vegetables. It activates the Nrf2 pathway, a master regulator of the antioxidant response, potentially enhancing Sall2 function by influencing cellular stress response mechanisms. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin is a natural polyphenolic compound known to regulate multiple signal transduction pathways. It might enhance Sall2 function through its effects on cellular signaling. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $46.00 $92.00 $117.00 | 3 | |
Salicylic acid is a plant hormone that can regulate plant immunity. Although its mechanisms in human cells are less understood, it has been shown to influence cellular processes that could enhance the function of Sall2. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Alpha-lipoic acid is an antioxidant that is known to modulate various signaling pathways, such as those involved in cellular redox balance, potentially leading to the functional activation of Sall2. | ||||||