Sall2 inhibitors represent a specific class of chemical compounds that have gained recognition in the field of molecular biology and gene regulation research. Sall2, or Sal-like protein 2, is a transcription factor that plays a pivotal role in regulating gene expression and developmental processes in various organisms, including humans. The term Sall2 inhibitors refers to a group of molecules meticulously designed to selectively target and modulate the activity of Sall2. These inhibitors serve as crucial tools in laboratory investigations, enabling researchers to explore the intricate molecular functions and cellular processes associated with Sall2.
Sall2 inhibitors typically function by interfering with the binding of Sall2 to its target DNA sequences or by modulating its interactions with co-factors and regulatory molecules. This interference can lead to alterations in gene expression patterns and downstream cellular processes influenced by Sall2, ultimately affecting various aspects of cellular biology and development. Researchers employ Sall2 inhibitors to gain insights into the physiological roles and molecular interactions of Sall2 within cells, aiming to advance our understanding of the fundamental mechanisms involved in gene regulation and embryonic development. Through the study of Sall2 inhibitors, scientists seek to unravel the complexities of developmental genetics, tissue patterning, and the broader field of molecular biology, contributing to our knowledge of how genes and transcription factors orchestrate the intricate process of embryogenesis and cellular differentiation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methyltransferase inhibitor, 5-Azacytidine could lead to demethylation of the Sall2 promoter, influencing its expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A inhibits histone deacetylases (HDACs), potentially affecting chromatin structure and Sall2 gene expression. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid is an HDAC inhibitor that can alter gene expression, possibly affecting Sall2 transcription. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat is another HDAC inhibitor that could conceivably modify chromatin to influence Sall2 expression patterns. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin A binds to GC-rich DNA sequences and could affect the transcription of genes like Sall2. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA and can inhibit RNA polymerase, potentially downregulating Sall2 transcription. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
Cyclopamine inhibits the Hedgehog signaling pathway, which might have downstream effects on Sall2 expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR signaling and could indirectly affect Sall2 expression via modulation of cell growth pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002, a PI3K inhibitor, may indirectly reduce Sall2 expression by altering cell survival and growth signals. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
As a potent kinase inhibitor, staurosporine could affect multiple pathways with potential downstream effects on Sall2 expression. | ||||||