S2P Activators
The class of chemicals known as S2P Activators encompasses a diverse set of compounds that can influence the activity of MBTPS2, also known as S2P, a membrane-bound zinc metalloprotease.
Thapsigargin and A23187 are compounds that elevate intracellular calcium levels. The shifts in calcium dynamics within the cell can subsequently influence signaling pathways where S2P plays a role. Tunicamycin acts by inhibiting N-linked glycosylation, a process that could modulate the activity or stability of S2P by affecting its post-translational modifications. Brefeldin A, on the other hand, disrupts the structure and function of the Golgi apparatus, a cellular location where S2P processing or activity may be significant. Another chemical, Phenylarsine oxide, obstructs protein transport between the endoplasmic reticulum and Golgi, which can have implications for the activity and function of S2P. Cerulenin's ability to inhibit lipid synthesis and the ionophores like Monensin and Nigericin, which disrupt cellular ion balance, serve as another layer of influence over processes related to S2P. FCCP, by uncoupling mitochondrial oxidative phosphorylation, alters cellular energetics that can indirectly influence S2P's role within the cell. Lastly, Progesterone, a steroid hormone, has the capability to regulate a broad spectrum of cellular pathways and can indirectly touch upon the functions or regulatory mechanisms tied to S2P.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Elevates intracellular calcium levels, which can influence signaling pathways that MBTPS2 may be involved in. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Inhibits N-linked glycosylation, which could modulate MBTPS2 activity indirectly by affecting its processing or stability. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Disrupts Golgi apparatus structure and function, possibly affecting the processing or activity of MBTPS2. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
Calcium ionophore that alters intracellular calcium levels, which can impact pathways related to MBTPS2. | ||||||
Phenylarsine oxide | 637-03-6 | sc-3521 | 250 mg | $40.00 | 4 | |
Inhibitor of protein transport between the endoplasmic reticulum and Golgi, which could influence MBTPS2 activity. | ||||||
Cerulenin (synthetic) | 17397-89-6 | sc-200827 sc-200827A sc-200827B | 5 mg 10 mg 50 mg | $158.00 $306.00 $1186.00 | 9 | |
Inhibits lipid synthesis and can affect cellular processes related to MBTPS2. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Sodium ionophore affecting cellular ion balance, which can have downstream effects on MBTPS2-related pathways. | ||||||
Nigericin sodium salt | 28643-80-3 | sc-201518A sc-201518 sc-201518B sc-201518C sc-201518D | 1 mg 5 mg 25 mg 1 g 5 g | $45.00 $110.00 $235.00 $6940.00 $26879.00 | 9 | |
Potassium ionophore that modulates intracellular ion levels, influencing pathways potentially connected to MBTPS2. | ||||||
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $92.00 $348.00 | 46 | |
Uncouples mitochondrial oxidative phosphorylation, which can alter cellular energetics and influence MBTPS2 activity. | ||||||
Progesterone | 57-83-0 | sc-296138A sc-296138 sc-296138B | 1 g 5 g 50 g | $20.00 $51.00 $292.00 | 3 | |
Steroid hormone that can regulate various cellular pathways, potentially influencing MBTPS2's function indirectly. | ||||||