Date published: 2026-2-14

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RUSC1 Activators

RUSC1 activators constitute a specialized class of chemical compounds that have garnered interest in the field of molecular biology and genetics. These compounds are designed to modulate the activity of RUSC1, a protein-coding gene that plays a role in various cellular processes. RUSC1, or RUN and SH3 domain containing 1, is characterized by its structural features, including RUN and SH3 domains, which are known to be involved in protein-protein interactions and cellular signaling pathways. RUSC1 activators function by targeting specific regulatory elements within the RUSC1 gene, often located in promoter or enhancer regions, with the primary aim of enhancing its transcription and subsequent translation into functional protein products.

The mechanisms by which RUSC1 activators exert their effects may vary, but their core objective is to act as molecular switches, amplifying the activity of RUSC1. Researchers are continually exploring the potential applications and implications of RUSC1 activation, striving to gain a deeper understanding of how this gene contributes to cellular processes, particularly in the context of protein-protein interactions and cellular signaling. This class of compounds holds promise for advancing our knowledge of gene regulation, particularly within the domain of RUN and SH3 domain-containing proteins, offering insights into the intricate mechanisms that govern cellular communication and the role of RUSC1 in various biological contexts. RUSC1 activators represent valuable tools in ongoing investigations within molecular biology, providing opportunities to uncover the complex roles that RUSC1 plays in cellular processes and its significance in protein-protein interactions and cellular signaling pathways.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium chloride can activate Wnt signaling pathway indirectly, which may lead to altered gene expression profiles, potentially including RUSC1.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-azacytidine, a DNA methylation inhibitor, could potentially increase RUSC1 expression by reducing methylation near its promoter region.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

As a histone deacetylase inhibitor, Trichostatin A can increase the acetylation of histones, leading to a more open chromatin state and potentially upregulating gene expression, including RUSC1.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

Another histone deacetylase inhibitor that could lead to changes in chromatin structure and potentially increase the expression of genes like RUSC1.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

By increasing intracellular cAMP levels, Forskolin can activate PKA signaling, which might influence RUSC1 expression through phosphorylation of transcription factors.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$63.00
$182.00
8
(1)

As a primary female sex hormone, beta-estradiol can regulate gene expression via estrogen receptors, which may include effects on RUSC1 expression.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

A synthetic glucocorticoid that may affect gene expression through glucocorticoid receptor-mediated transcription, potentially altering RUSC1 expression.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

A derivative of vitamin A that modulates gene expression by activating retinoic acid receptors, which could potentially lead to changes in RUSC1 expression.

Isoproterenol Hydrochloride

51-30-9sc-202188
sc-202188A
100 mg
500 mg
$28.00
$38.00
5
(0)

A beta-adrenergic agonist that could lead to changes in gene expression via the cAMP-PKA signaling pathway, potentially affecting RUSC1 expression.

Dimethyl Sulfoxide (DMSO)

67-68-5sc-202581
sc-202581A
sc-202581B
100 ml
500 ml
4 L
$31.00
$117.00
$918.00
136
(6)

Solvent often used to facilitate cell permeability, which might incidentally influence gene expression patterns, including RUSC1.