ROGDI Activators
ROGDI Activators are a diverse range of compounds that can enhance the functional activity of ROGDI through various signaling pathways. These include Resveratrol, a Sirtuin 1 activator that enhances ROGDI function by increasing its stability and nuclear localization; Curcumin and Honokiol, NF-kB pathway inhibitors that enhance ROGDI function by stabilizing it; and Epigallocatechin Gallate (EGCG), a PI3K/Akt pathway modulator that regulates the cellular localization and stability of ROGDI.
Quercetin and Fisetin are flavonoids that inhibit the JNK pathway, leading to enhanced ROGDI function. Berberine and Metformin activate the AMPK pathway, which has been implicated in the regulation of ROGDI. Rosiglitazone, a PPAR-gamma activator, enhances ROGDI function by increasing its stability. Spermidine, a compound that activates the mTORC1 pathway, enhances ROGDI function by regulating it. Capsaicin, a TRPV1 activator, enhances the function of ROGDI by modulating its associated pathway. Naringenin, similar to Curcumin and Honokiol, inhibits the NF-kB pathway and enhances the function of ROGDI. Therefore, these compounds can act on various elements of cellular signaling, enhancing the activity of ROGDI.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is a potent Sirtuin 1 activator. Sirt1 is known to regulate several cellular processes including cell survival and neuroprotection. It can enhance the function of ROGDI by increasing its stability and nuclear localization. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is a compound that can inhibit the NF-kB pathway. As NF-kB pathway is implicated in the regulation of ROGDI, its inhibition might lead to enhanced stability and function of ROGDI. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a potent antioxidant known to modulate the PI3K/Akt pathway. This pathway has been implicated in the cellular localization and stability of ROGDI. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid that inhibits the JNK pathway. The JNK pathway is known to regulate the function of ROGDI, and its inhibition could potentially enhance ROGDI function. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine is a compound known to activate the AMPK pathway, which has been implicated in the regulation of ROGDI. Activation of this pathway might lead to enhanced function of ROGDI. | ||||||
Metformin-d6, Hydrochloride | 1185166-01-1 | sc-218701 sc-218701A sc-218701B | 1 mg 5 mg 10 mg | $292.00 $822.00 $1540.00 | 1 | |
Metformin is known to activate the AMPK pathway. As AMPK pathway is involved in the regulation of ROGDI, its activation could potentially enhance ROGDI function. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
Rosiglitazone is a PPAR-gamma activator. PPAR-gamma activation has been associated with increased stability and function of ROGDI. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $57.00 $607.00 $176.00 | ||
Spermidine activates the mTORC1 pathway, which is known to regulate ROGDI. Activation of this pathway could enhance the function of ROGDI. | ||||||
Honokiol | 35354-74-6 | sc-202653 sc-202653A | 10 mg 25 mg | $118.00 $178.00 | 4 | |
Honokiol is known to inhibit the NF-kB pathway. As NF-kB pathway is implicated in ROGDI regulation, its inhibition might lead to enhanced stability and function of ROGDI. | ||||||
Fisetin | 528-48-3 | sc-276440 sc-276440A sc-276440B sc-276440C sc-276440D | 50 mg 100 mg 500 mg 1 g 100 g | $52.00 $79.00 $104.00 $156.00 $2913.00 | 7 | |
Fisetin is a flavonoid that inhibits the JNK pathway. The JNK pathway is known to regulate ROGDI, and its inhibition could potentially enhance ROGDI function. | ||||||