RNF149 Activators
Items 1 to 10 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG132 is a peptide aldehyde that inhibits proteasome activity, thereby indirectly affecting RNF149 by preventing the degradation of its ubiquitinated substrates. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib is a proteasome inhibitor similar to MG132, preventing proteasome-mediated protein degradation and leading to the stabilization and accumulation of RNF149. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
Geldanamycin disrupts Hsp90 chaperone function, indirectly activating RNF149 by interfering with Hsp90-mediated protein stability. | ||||||
Lactacystin | 133343-34-7 | sc-3575 sc-3575A | 200 µg 1 mg | $165.00 $575.00 | 60 | |
Lactacystin is a natural product that irreversibly inhibits proteasomal activity, impacting the function of RNF149 indirectly. | ||||||
Epoxomicin | 134381-21-8 | sc-201298C sc-201298 sc-201298A sc-201298B | 50 µg 100 µg 250 µg 500 µg | $134.00 $215.00 $440.00 $496.00 | 19 | |
Epoxomicin is a natural product that selectively inhibits the chymotrypsin-like activity of the proteasome, similarly affecting RNF149. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
Nutlin-3 inhibits the p53-MDM2 interaction, potentially influencing RNF149 through p53 signaling pathways, as p53 can modulate protein degradation and cellular processes. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
H2O2 induces oxidative stress and activates RNF149 indirectly through redox signaling, promoting post-translational modifications of proteins, including RNF149. | ||||||
MLN 4924 | 905579-51-3 | sc-484814 | 1 mg | $280.00 | 1 | |
MLN4924 inhibits NEDD8-activating enzyme, essential for neddylation that regulates E3 ligase activity, thus indirectly impacting RNF149. | ||||||
Ubiquitin E1 Inhibitor, PYR-41 | 418805-02-4 | sc-358737 | 25 mg | $360.00 | 4 | |
PYR-41 is a cell-permeable compound that inhibits ubiquitin-activating enzyme E1, indirectly affecting ubiquitination by RNF149. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Tunicamycin induces ER stress by inhibiting N-linked glycosylation, indirectly affecting RNF149 expression and activity as part of the ER stress response. | ||||||