Date published: 2025-10-30

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Rhox6 Activators

The chemical class known as Rhox6 Activators encompasses a diverse range of compounds that share the common ability to initiate a cellular cascade resulting in the activation of the Rhox6 protein. These activators work by targeting various signaling pathways and cellular mechanisms that ultimately contribute to changes in gene expression. One of the primary methods by which these activators function is by modulating the cellular concentration of second messengers such as cAMP. This modulation can activate key protein kinases that are crucial in the phosphorylation of specific transcription factors or other proteins that interact with the transcriptional machinery. By influencing these kinases, the activators can indirectly influence the transcriptional activity of genes, including those regulated by Rhox6.

In addition to affecting second messenger systems, certain activators in this class function by altering the epigenetic landscape of the cell. They achieve this by inhibiting enzymes responsible for DNA methylation or histone deacetylation, leading to changes in chromatin structure that facilitate transcription factor binding and gene expression. Others interact with cellular receptors and influence gene transcription via hormone-like signaling mechanisms. Some activators also impact cellular differentiation and proliferation pathways, which can have downstream effects on the expression of a multitude of genes, including transcription factors. The precise molecular pathways through which these activators exert their influence are complex and involve a multitude of intracellular interactions and feedback mechanisms. As a result, the activators within the Rhox6 Activators class are not only diverse in their structure but also in the mechanisms through which they modulate cellular processes to foster an environment conducive to Rhox6 activation.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Influences gene transcription and is known to regulate homeobox genes during development, which could possibly activate Rhox6.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Activates adenylyl cyclase, raising cAMP levels, which can lead to the activation of protein kinase A (PKA) and could possibly activate Rhox6 through transcription factor modulation.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A DNA methyltransferase inhibitor that can cause DNA demethylation, potentially leading to the activation of gene expression, which could possibly activate Rhox6.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

An inhibitor of histone deacetylases (HDACs) that can lead to a more open chromatin structure and could possibly activate Rhox6 by increasing gene expression.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

A polyphenol found in green tea that can modulate various signaling pathways and could possibly activate Rhox6 by influencing gene expression.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

An HDAC inhibitor that can lead to histone hyperacetylation, affecting gene transcription, which could possibly activate Rhox6.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

Activates protein kinase C (PKC), which can lead to changes in transcription factor activity and could possibly activate Rhox6 by altering gene expression.

Adenosine 3′,5′-cyclic monophosphate

60-92-4sc-217584
sc-217584A
sc-217584B
sc-217584C
sc-217584D
sc-217584E
100 mg
250 mg
5 g
10 g
25 g
50 g
$114.00
$175.00
$260.00
$362.00
$617.00
$1127.00
(1)

A cAMP analog that can permeate cell membranes and mimic the action of cAMP, potentially affecting PKA and could possibly activate Rhox6 by influencing gene transcription.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$62.00
$178.00
8
(1)

A hormone that can bind estrogen receptors and could possibly activate Rhox6 by influencing gene expression, including the regulation of transcription factors.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Inhibits glycogen synthase kinase 3 (GSK-3) and could possibly activate Rhox6 by affecting Wnt signaling and gene transcription.