resistin-like γ Inhibitors
Resistin-like γ inhibitors are molecules that target and modulate the activity of resistin-like molecule gamma (RELMγ), a member of the resistin-like family of proteins. These proteins belong to a broader group of cysteine-rich secretory proteins and play roles in metabolic, inflammatory, and immune-related processes. Resistin-like γ specifically shares structural similarities with resistin, including a conserved pattern of cysteine residues, which form disulfide bridges that stabilize its three-dimensional structure. This structural framework is critical for its biological interactions, allowing resistin-like γ to participate in various signaling pathways. The regulation of resistin-like γ is influenced by several factors, including cytokines and environmental stimuli, which modulate its production and secretion.
Inhibitors of resistin-like γ are designed to bind to or otherwise interfere with its active sites or structural domains, preventing the protein from engaging with its natural receptors or signaling partners. These inhibitors may work by blocking the functional interfaces on the protein, thereby impeding its ability to initiate or propagate signaling cascades. Additionally, resistin-like γ inhibitors may disrupt the protein's conformational stability, making it more prone to degradation or less effective in binding its targets. The specificity and efficacy of these inhibitors depend on their ability to selectively interact with resistin-like γ without affecting closely related proteins within the resistin-like family. Understanding the binding mechanisms and structural nuances of these inhibitors is crucial for elucidating their broader impact on biochemical pathways, particularly those associated with resistin-like γ's roles in homeostatic processes.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin may inhibit the expression of resistin like gamma by modulating various signaling pathways involved in inflammation and immune response. It has been shown to downregulate the activity of transcription factors and cytokines that are involved in the regulation of resistin like gamma. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol has the potential to inhibit the expression of resistin like gamma due to its anti-inflammatory properties. It can modulate the activity of nuclear factor-kappa B (NF-kB) and other pro-inflammatory mediators, thus suppressing the expression of resistin like gamma, which is implicated in inflammatory processes. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein may inhibit the expression of resistin like gamma by interfering with the signaling pathways involved in inflammatory responses. It has been shown to modulate the activity of kinases and transcription factors that regulate the expression of resistin like gamma, thereby exerting an inhibitory effect on its production. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is capable of inhibiting the expression of resistin like gamma by modulating the activity of various inflammatory mediators and transcription factors. It can downregulate the expression of resistin like gamma by interfering with the signaling pathways involved in the regulation of inflammatory responses and immune function. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Berberine may inhibit the expression of resistin like gamma through its anti-inflammatory properties. It can modulate the activity of specific kinases and transcription factors involved in the regulation of resistin like gamma, thus exerting a suppressive effect on its expression, which is closely associated with inflammatory processes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin gallate has the potential to inhibit the expression of resistin like gamma by modulating the activity of inflammatory signaling pathways and transcription factors. It can downregulate the expression of resistin like gamma by interfering with the regulation of immune responses and inflammatory processes, where resistin like gamma plays a role. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $26.00 $50.00 $99.00 $150.00 $1887.00 | 40 | |
Luteolin may inhibit the expression of resistin like gamma by interfering with the activity of specific inflammatory mediators and transcription factors. It can downregulate the expression of resistin like gamma by modulating the signaling pathways involved in immune responses and inflammation, where resistin like gamma is implicated. | ||||||
Fisetin | 528-48-3 | sc-276440 sc-276440A sc-276440B sc-276440C sc-276440D | 50 mg 100 mg 500 mg 1 g 100 g | $51.00 $77.00 $102.00 $153.00 $2856.00 | 7 | |
Fisetin has been shown to inhibit the expression of resistin like gamma by modulating the activity of inflammatory signaling pathways and transcription factors. It can interfere with the regulation of immune responses and inflammatory processes, thus exerting a suppressive effect on the expression of resistin like gamma. | ||||||
Baicalein | 491-67-8 | sc-200494 sc-200494A sc-200494B sc-200494C | 10 mg 100 mg 500 mg 1 g | $31.00 $41.00 $159.00 $286.00 | 12 | |
Baicalein is capable of inhibiting the expression of resistin like gamma by modulating the activity of specific inflammatory mediators and transcription factors. It can downregulate the expression of resistin like gamma by interfering with the signaling pathways involved in immune responses and inflammation, where resistin like gamma plays a role. | ||||||
Silybin | 22888-70-6 | sc-202812 sc-202812A sc-202812B sc-202812C | 1 g 5 g 10 g 50 g | $54.00 $112.00 $202.00 $700.00 | 6 | |
Silibinin may inhibit the expression of resistin like gamma through its anti-inflammatory properties. It can modulate the activity of specific kinases and transcription factors involved in the regulation of resistin like gamma, thus exerting a suppressive effect on its expression, which is closely associated with inflammatory processes. | ||||||