PRSS50 Activators
PRSS50 Activators constitute a diverse set of chemicals that can modulate the activity or expression of the PRSS50 protein, a member of the serine protease family. These activators function through either direct action on PRSS50 or by influencing related cellular signaling pathways.
Forskolin, for instance, elevates cyclic AMP levels, which can influence PRSS50 expression, given the known modulatory effects of cAMP on cellular processes. EGF, on the other hand, regulates numerous cell signaling pathways that can directly or indirectly affect PRSS50 transcription or stability. PMA, a well-known activator of protein kinase C (PKC), can impact serine protease pathways such as PRSS50 via PKC-mediated cellular responses. Pathway-specific inhibitors like U0126, LY294002, SB203580, SP600125, and PD98059 target components of the MAPK and PI3K/AKT pathways, demonstrating the intricate interconnectedness of cellular signaling. Their influence on these critical pathways can lead to downstream effects on proteins, including PRSS50. Rapamycin, an mTOR pathway modulator, serves as a testament to the expansive cellular influence of mTOR, possibly affecting PRSS50 activity. Wortmannin, similar to LY294002, affects the PI3K/AKT pathway, revealing the importance of this signaling axis in the context of PRSS50 modulation. Lastly, calcium-modulating agents like Ionomycin and 2-APB underscore the pivotal role of calcium in cell signaling. Their ability to alter intracellular calcium levels can set off a cascade of cellular responses that can, in turn, influence PRSS50 activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin can elevate cyclic AMP (cAMP) levels, which can potentially influence PRSS50 expression or activity as cAMP signaling is known to modulate various cellular processes including those associated with serine proteases. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which is involved in a multitude of cellular pathways. Activation of PKC can lead to modulations in serine protease pathways, potentially affecting PRSS50 activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
This compound inhibits PI3K, a critical component in the PI3K/AKT pathway. By altering this pathway, it can have downstream effects that might influence PRSS50 activity, given the pathway's vast cellular influence. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor. The MAPK pathway intersects with numerous cellular processes, and its modulation can affect serine proteases like PRSS50 either directly or via interconnected pathways. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
As a JNK inhibitor, SP600125 impacts the JNK pathway, which plays roles in various cellular processes including those associated with serine proteases. This could lead to indirect modulation of PRSS50 activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor. By modulating the mTOR pathway, it can influence cellular processes and pathways associated with PRSS50, given the extensive roles of mTOR in cells. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin, another PI3K inhibitor, can modify the PI3K/AKT pathway, potentially influencing downstream processes or pathways linked to PRSS50 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is an inhibitor of MEK, a part of the MAPK pathway. Through its modulation of MAPK signaling, it might indirectly impact pathways and processes tied to PRSS50 activity. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Ionomycin increases intracellular calcium concentrations. Elevated calcium can activate various calcium-dependent proteins and pathways, potentially having a downstream effect on PRSS50 activity. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $27.00 $52.00 | 37 | |
2-APB modulates intracellular calcium levels and can also affect IP3 receptors. Given the critical role of calcium in cellular signaling, this compound might indirectly influence PRSS50 activity via calcium-dependent pathways. | ||||||