PNPLA7 Activators
The list of chemicals thought to indirectly activate PNPLA7 primarily focuses on modulating lipid metabolism and signaling pathways. Oleic Acid, for instance, boosts triglyceride synthesis and can activate PNPLA7, as this enzyme plays a role in triglyceride hydrolysis. Fenofibrate acts as a PPARα agonist, promoting fatty acid oxidation. This increased oxidation rate necessitates higher activity of enzymes responsible for lipid mobilization, including PNPLA7. Lysophosphatidic Acid and Sphingosine-1-phosphate are other crucial lipid signaling molecules that influence lipid storage and turnover, thereby affecting PNPLA7 activation.
Curcumin and Retinoic Acid add another layer to this chemical classification. These compounds modulate lipid metabolism through different receptor-mediated pathways. Curcumin has a broad impact on lipid metabolism and can thereby lead to the activation of PNPLA7 for triglyceride hydrolysis. Retinoic Acid, through its influence on retinoid receptors, also plays a role in lipid metabolism, leading to increased PNPLA7 activity. Both of these compounds, among others, serve to maintain lipid homeostasis, and their mechanisms of action can lead to the indirect activation of PNPLA7.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $36.00 $102.00 $569.00 $1173.00 | 10 | |
Unsaturated fatty acid that elevates triglyceride synthesis, which can result in activation of PNPLA7 for hydrolysis. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
Activates sphingolipid signaling, affecting lipid storage and potentially requiring PNPLA7 for lipid turnover. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
PPARα agonist that can promote fatty acid oxidation, which indirectly calls for PNPLA7 activity in lipid mobilization. | ||||||
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $96.00 $334.00 | 50 | |
Engages lipid signaling, potentially activating PNPLA7 for phospholipid hydrolysis. | ||||||
Arachidonic Acid (20:4, n-6) | 506-32-1 | sc-200770 sc-200770A sc-200770B | 100 mg 1 g 25 g | $90.00 $235.00 $4243.00 | 9 | |
Essential fatty acid that could necessitate PNPLA7 for lipid processing. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Modulates lipid metabolism and could indirectly lead to PNPLA7 activation for triglyceride hydrolysis. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Facilitates glucose uptake and indirectly affects lipid storage, which may activate PNPLA7 for lipid turnover. | ||||||
Cerulenin (synthetic) | 17397-89-6 | sc-200827 sc-200827A sc-200827B | 5 mg 10 mg 50 mg | $158.00 $306.00 $1186.00 | 9 | |
Fatty acid synthase inhibitor, which can activate PNPLA7 as a compensatory response for lipid mobilization. | ||||||
Palmitoyl-L-carnitine Chloride | 18877-64-0 | sc-205789 sc-205789A sc-205789B | 5 mg 25 mg 100 mg | $138.00 $505.00 $2045.00 | ||
Increases fatty acid oxidation, thereby potentially activating PNPLA7 for triglyceride hydrolysis. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Affects lipid metabolism and fatty acid storage, potentially activating PNPLA7 in the lipid turnover process. | ||||||