Molecular structure of Palmitoyl-L-carnitine Chloride, CAS Number: 18877-64-0
Palmitoyl-L-carnitine Chloride (CAS 18877-64-0)
Alternate Names:
O-Palmitoyl-L-carnitine chloride
Application:
Palmitoyl-L-carnitine Chloride is an inhibitor of protein kinases
CAS Number:
18877-64-0
Purity:
≥98%
Molecular Weight:
436.10
Molecular Formula:
C23H45NO4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Palmitoyl-L-carnitine chloride is a chemical compound that belongs to the class of acylcarnitines. Its chloride salt form enhances its stability and solubility. It is derived from the amino acid L-carnitine, which plays a vital role in energy metabolism in the body. Palmitoyl-L-carnitine specifically contains a palmitoyl group attached to the L-carnitine molecule. Acylcarnitines, including palmitoyl-L-carnitine, are involved in the transport of long-chain fatty acids into the mitochondria, where they undergo beta-oxidation to generate energy. This process is for the utilization of fatty acids as a fuel source.
Palmitoyl-L-carnitine Chloride (CAS 18877-64-0) References
- Effects of in vivo treatment of rats with trimethyltin chloride on respiratory properties of rat liver mitochondria. | Skarning, CR., et al. 2002. Biochem Pharmacol. 64: 657-67. PMID: 12167485
- Some aspects of fatty acid oxidation in isolated fat-cell mitochondria from rat. | Harper, RD. and Saggerson, ED. 1975. Biochem J. 152: 485-94. PMID: 1227502
- Enhanced bioavailability of cefoxitin using palmitoyl L-carnitine. I. Enhancer activity in different intestinal regions. | Sutton, SC., et al. 1992. Pharm Res. 9: 191-4. PMID: 1553340
- Using Isolated Mitochondria from Minimal Quantities of Mouse Skeletal Muscle for High throughput Microplate Respiratory Measurements. | Boutagy, NE., et al. 2015. J Vis Exp. e53216. PMID: 26555567
- Isolation of Mitochondria from Minimal Quantities of Mouse Skeletal Muscle for High Throughput Microplate Respiratory Measurements. | Boutagy, NE., et al. 2015. J Vis Exp.. PMID: 26650566
- Amino acid and lipid associated plasma metabolomic patterns are related to healthspan indicators with ageing. | Johnson, LC., et al. 2018. Clin Sci (Lond). 132: 1765-1777. PMID: 29914938
- Subcellular localization and properties of cytochrome P-450 and UDP glucuronosyltransferase in the rainbow trout kidney. | Pesonen, M. and Andersson, T. 1987. Biochem Pharmacol. 36: 823-9. PMID: 3105537
- Undesirable effects of chemical inhibitors of NAD(P)+ transhydrogenase on mitochondrial respiratory function. | Bicego, R., et al. 2020. Arch Biochem Biophys. 692: 108535. PMID: 32781052
- Skeletal muscle mitochondrial fragmentation and impaired bioenergetics from nutrient overload are prevented by carbon monoxide. | Gasier, HG., et al. 2020. Am J Physiol Cell Physiol. 319: C746-C756. PMID: 32845721
- Short-term exposure to a clinical dose of metformin increases skeletal muscle mitochondrial H2O2 emission and production in healthy, older adults: A randomized controlled trial. | McKenzie, AI., et al. 2022. Exp Gerontol. 163: 111804. PMID: 35405248
- Ammonium inhibition of fatty acid oxidation in rat liver mitochondria. A possible cause of fatty liver in Reye's syndrome and urea cycle defects. | Maddaiah, VT. 1985. Biochem Biophys Res Commun. 127: 565-70. PMID: 3977937
- Mitochondria from the hepatopancreas of the marine clam Mercenaria mercenaria: substrate preferences and salt and pH effects on the oxidation of palmitoyl-L-carnitine and succinate. | Ballantyne, JS. and Storey, KB. 1984. J Exp Zool. 230: 165-74. PMID: 6736891
- Effect of L-carnitine and acylcarnitine derivatives on the proliferation and monoclonal antibody production of mouse hybridoma cells in culture. | Berchiche, L., et al. 1994. J Biotechnol. 34: 175-83. PMID: 7764849
Inhibitor of:
Enzyme.Activator of:
LIPM, PNPLA7, and PRELI.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Palmitoyl-L-carnitine Chloride, 5 mg | sc-205789 | 5 mg | $138.00 | |||
Palmitoyl-L-carnitine Chloride, 25 mg | sc-205789A | 25 mg | $505.00 | |||
Palmitoyl-L-carnitine Chloride, 100 mg | sc-205789B | 100 mg | $2045.00 |