PLEKHA6 Activators
Plekha6 Activators represent a specialized class of chemical compounds that have garnered attention in the field of molecular biology and cellular research. These activators are designed to modulate the activity of the PLEKHA6 gene, where PLEKHA6 stands for Pleckstrin Homology Domain-Containing Family A Member 6. The PLEKHA6 gene codes for a protein that contains pleckstrin homology (PH) domains, which are known for their involvement in cell signaling and membrane interactions.
The mechanism of action of Plekha6 Activators typically involves their interaction with specific regulatory elements within the PLEKHA6 gene, such as promoter regions or enhancer sequences. These interactions facilitate the upregulation of gene transcription, resulting in heightened synthesis of the PLEKHA6 protein. While the exact biological functions of PLEKHA6 are still under investigation, researchers are actively exploring its potential roles in cellular processes, including intracellular signaling, membrane dynamics, or potential contributions to various cellular responses. As our understanding of PLEKHA6 activation continues to evolve, the development and refinement of Plekha6 Activators offer the prospect of advancing our comprehension of molecular biology, molecular mechanisms, and the broader implications of PLEKHA6 in cellular functionality, potentially revealing novel aspects of cell signaling and membrane interactions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, through retinoic acid receptors, affects transcription of numerous genes and could potentially influence the expression of PLEKHA6. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin raises intracellular cAMP levels, which can activate CREB and modulate gene transcription, potentially inducing PLEKHA6 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
TSA, another histone deacetylase inhibitor, can alter chromatin structure and increase the expression of various genes, potentially PLEKHA6. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine inhibits DNA methylation, potentially leading to the activation of silenced genes, which could include PLEKHA6. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Beta-estradiol can modulate gene expression via estrogen receptors, which may hypothetically result in the upregulation of PLEKHA6. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, a tyrosine kinase inhibitor and phytoestrogen, could affect gene expression profiles, potentially influencing PLEKHA6. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Similar to butyrate, sodium butyrate is a HDAC inhibitor and could lead to increased transcription of genes such as PLEKHA6. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane may affect gene expression by activating NRF2 and influencing antioxidant response element-mediated transcription, possibly affecting PLEKHA6. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibitor | 935693-62-2 free base | sc-202651 | 5 mg | $148.00 | 4 | |
BIX-01294 is a G9a histone methyltransferase inhibitor that could alter chromatin states and gene expression, possibly including PLEKHA6. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
RG108 is a DNA methyltransferase inhibitor, which can lead to demethylation and activation of gene promoters, potentially affecting PLEKHA6. | ||||||