The chemical class of PiT1 Inhibitors can be considered as a diverse group of compounds that have the ability to interfere with the function of the PiT1 protein or the cellular processes it is involved in. These chemicals do not necessarily act directly on PiT1, but their actions can modify the signaling pathways that PiT1 is part of, thereby influencing its function. This group includes kinase inhibitors, phosphatase inhibitors, and other types of compounds known to affect cellular signaling.
Kinase inhibitors in this class, such as Staurosporine, LY294002, PD98059, U0126, Genistein, Quercetin, Dasatinib, SP600125, SB203580, and PP2, can interfere with the activity of various kinases. As kinases are responsible for the phosphorylation of proteins, a key post-translational modification in cellular signaling, these inhibitors can interfere with the PiT1-associated cellular processes by affecting the activity of kinases that may potentially phosphorylate PiT1 or other proteins involved in the same signaling cascades.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
An indolocarbazole that inhibits various kinases, including protein kinase C, which can interfere with PiT1-associated cellular processes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A potent inhibitor of phosphoinositide 3-kinases (PI3K), which may indirectly affect PiT1 by altering kinase-dependent pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A selective inhibitor of MEK, which could influence PiT1 function by altering mitogen-activated protein kinase (MAPK) signaling. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
A tyrosine kinase inhibitor that can interfere with the phosphorylation processes associated with PiT1. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
A flavonoid that has been found to inhibit a wide range of kinases and may interfere with PiT1-associated kinase activity. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
A multi-target kinase inhibitor that can interfere with protein phosphorylation pathways associated with PiT1. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An anthrapyrazolone inhibitor that selectively inhibits JNK, thereby potentially disrupting PiT1-related processes. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A selective p38 MAPK inhibitor that may indirectly affect PiT1 function. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
A potent and selective Src family tyrosine kinase inhibitor, which can interfere with PiT1 function. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
An irreversible inhibitor of IκBα phosphorylation, which can affect NF-κB associated PiT1 processes. | ||||||