Date published: 2026-4-24

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PIAS Antibodies

Santa Cruz Biotechnology delivers a wide array of PIAS monoclonal antibodies for advanced research in cellular signaling and gene regulation. PIAS monoclonal antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PIAS proteins, or Protein Inhibitors of Activated STAT, are key regulators of signal transducer and activator of transcription (STAT) signaling pathways, which mediate cellular responses to cytokines and growth factors. Through modulation of STAT proteins, PIAS proteins influence immune response, cell growth, and differentiation, playing important roles in normal physiology and disease states, including cancer and autoimmune disorders. PIAS proteins participate in various cellular mechanisms beyond STAT regulation, including transcriptional control and protein modification. Understanding PIAS protein function has significant implications for developing targeted therapies in multiple disease contexts. Research involving PIAS proteins continues to reveal new insights into cellular regulation and disease mechanisms. PIAS monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance scientific understanding of cellular processes and potential therapeutic applications.

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PIAS Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PIAS 1 Antibody (F-1)

sc-365127mouse IgG3 κ627-651 (h)WB, IP, IF, ELISAm, r, h
2
(3)

PIAS 1/3 Antibody (F-3)

sc-271172mouse IgG1 κ14-43 (h)WB, IP, IF, ELISAm, r, h
1
(1)

PIAS 3 Antibody (C-12)

sc-46682mouse IgG1 κ451-619 (h)WB, IP, IF, ELISAm, r, h
13
(7)

PIAS 3 Antibody (E-3)

sc-48339mouse IgG2a κ551-619 (h)WB, IP, IF, ELISAm, r, h
1
(3)

PIASx Antibody (D-12)

sc-166494mouse IgG2a κ521-540 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(2)

PIASy Antibody (C-11)

sc-166706mouse IgG1 κ97-114 (h)WB, IP, IF, ELISAh
5
(4)

PIASy Antibody (F-9)

sc-166744mouse IgG3 κ80-120 (h)WB, IP, IF, ELISAm, r, h
2
(1)

PIASy Antibody (H-9)

sc-376315mouse IgG1 κ61-130 (m)WB, IP, IF, ELISAm, r, h

new

(1)

PIAS CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PIASx CRISPR/Cas9 KO Plasmid (h)

sc-403954hGene KnockoutGFP0
(0)

PIASx CRISPR/Cas9 KO Plasmid (m)

sc-421655mGene KnockoutGFP0
(0)

PIASy CRISPR/Cas9 KO Plasmid (h)

sc-403125hGene KnockoutGFP0
(0)

PIASy Double Nickase Plasmid (h)

sc-403125-NIChGene KnockoutPuromycin0
(0)

PIAS 1 Double Nickase Plasmid (h)

sc-402407-NIChGene KnockoutPuromycin0
(0)

PIAS CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PIASx CRISPR Activation Plasmid (h)

sc-403954-ACThGene ActivationPuro, Blast, Hygro0
(0)

PIASy CRISPR Activation Plasmid (h)

sc-403125-ACThGene ActivationPuro, Blast, Hygro0
(0)

PIAS 1 CRISPR Activation Plasmid (h)

sc-402407-ACThGene ActivationPuro, Blast, Hygro0
(0)

PIAS 3 CRISPR Activation Plasmid (h)

sc-401406-ACThGene ActivationPuro, Blast, Hygro0
(0)

PIAS 3 CRISPR Activation Plasmid (h2)

sc-401406-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PIAS siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PIASx siRNA (h)

sc-40849hGene SilencingN/A0
(0)

PIASx shRNA Plasmid (h)

sc-40849-SHhGene SilencingPuromycin0
(0)

PIASx shRNA (h) Lentiviral Particles

sc-40849-VhGene SilencingPuromycin0
(0)

PIASx siRNA (m)

sc-40850mGene SilencingN/A0
(0)

PIASx shRNA Plasmid (m)

sc-40850-SHmGene SilencingPuromycin0
(0)

PIASx shRNA (m) Lentiviral Particles

sc-40850-VmGene SilencingPuromycin0
(0)

PIASy siRNA (h)

sc-40851hGene SilencingN/A
2
(0)

PIASy shRNA Plasmid (h)

sc-40851-SHhGene SilencingPuromycin
2
(0)

PIASy shRNA (h) Lentiviral Particles

sc-40851-VhGene SilencingPuromycin
2
(0)

PIASy siRNA (m)

sc-40852mGene SilencingN/A0
(0)

PIASy shRNA Plasmid (m)

sc-40852-SHmGene SilencingPuromycin0
(0)

PIASy shRNA (m) Lentiviral Particles

sc-40852-VmGene SilencingPuromycin0
(0)

PIAS 1 siRNA (h)

sc-36219hGene SilencingN/A
2
(0)

PIAS 1 shRNA Plasmid (h)

sc-36219-SHhGene SilencingPuromycin
2
(0)

PIAS 1 shRNA (h) Lentiviral Particles

sc-36219-VhGene SilencingPuromycin
2
(0)

PIAS 1 siRNA (m)

sc-36220mGene SilencingN/A
4
(0)

PIAS 1 shRNA Plasmid (m)

sc-36220-SHmGene SilencingPuromycin
4
(0)

PIAS 1 shRNA (m) Lentiviral Particles

sc-36220-VmGene SilencingPuromycin
4
(0)

PIAS 3 siRNA (h)

sc-37005hGene SilencingN/A
5
(0)

PIAS 3 shRNA Plasmid (h)

sc-37005-SHhGene SilencingPuromycin
5
(0)

PIAS 3 shRNA (h) Lentiviral Particles

sc-37005-VhGene SilencingPuromycin
5
(0)

PIAS 3 siRNA (m)

sc-37006mGene SilencingN/A
1
(0)

PIAS 3 shRNA Plasmid (m)

sc-37006-SHmGene SilencingPuromycin
1
(0)

PIAS 3 shRNA (m) Lentiviral Particles

sc-37006-VmGene SilencingPuromycin
1
(0)

PIAS 1/3 siRNA (h)

sc-44013hGene SilencingN/A0
(0)

PIAS 1/3 shRNA Plasmid (h)

sc-44013-SHhGene SilencingPuromycin0
(0)

PIAS 1/3 shRNA (h) Lentiviral Particles

sc-44013-VhGene SilencingPuromycin0
(0)