Periphilin 1 is a protein encoded by the "PPHLN1" gene in humans. It is involved in multiple cellular processes, particularly in the formation and maintenance of the cellular cytoskeleton and in the regulation of gene expression.As its name suggests, periphilin 1 is localized primarily in the periphery of the cell, where it interacts with various components of the cytoskeleton. The cytoskeleton is a network of fibers that provides structural support to the cell, facilitates cellular movement, and plays a role in intracellular transport and cell division. By interacting with the cytoskeleton, periphilin 1 contributes to maintaining the structural integrity and dynamic nature of cells.
In addition to its structural role, periphilin 1 is involved in the regulation of gene expression. It has been found to associate with transcription factors and components of the transcription machinery, suggesting a role in modulating the transcription of specific genes. This regulation of gene expression is vital for various cellular functions, including differentiation, response to external stimuli, and cell cycle control.Periphilin 1 has also been studied in the context of its involvement in certain pathological conditions. Alterations in its expression or function have been associated with some skin disorders, where it may affect the structure and function of epidermal cells.Overall, periphilin 1 is a multifunctional protein with roles in maintaining cellular structure and regulating gene expression. Its diverse functions highlight its importance in fundamental cellular processes and its relevance in certain diseases.
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产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
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5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
作为一种 DNA 甲基转移酶抑制因子,5-氮杂胞苷可改变染色质结构,并可间接影响 Periphilin 1 在转录抑制物中的作用。 | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
作为组蛋白去乙酰化酶抑制剂,Trichostatin A 会影响染色质重塑,从而可能影响 Periphilin 1 的功能。 | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
另一种组蛋白去乙酰化酶抑制剂 SAHA 可能会影响染色质结构,并间接影响 Periphilin 1 的活性。 | ||||||
RGFP966 | 1357389-11-7 | sc-507300 | 5 mg | $115.00 | ||
HDAC3 特异性抑制剂 RGFP966 可间接影响染色质结构和 Periphilin 1 的功能。 | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
选择性 HDAC 抑制剂 MS-275 可影响染色质重塑,并可能影响 Periphilin 1 的活性。 | ||||||
Histone Lysine Methyltransferase Inhibitor 抑制剂 | 935693-62-2 free base | sc-202651 | 5 mg | $148.00 | 4 | |
G9a组蛋白甲基转移酶抑制剂BIX-01294可改变组蛋白甲基化,从而可能影响Periphilin 1的功能。 | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $260.00 $925.00 | 5 | |
组蛋白乙酰转移酶抑制剂 C646 可通过影响组蛋白乙酰化和染色质结构间接影响 Periphilin 1。 | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
BET 溴链抑制剂 JQ1 可影响染色质结构,并间接影响 Periphilin 1 的活性。 | ||||||
Methylstat | 1310877-95-2 | sc-507374 | 10 mg | $480.00 | ||
含 Jumonji C 结构域的组蛋白去甲基化酶抑制剂 Methylstat 可通过影响组蛋白甲基化间接影响 Periphilin 1 的活性。 | ||||||
Chaetocin | 28097-03-2 | sc-200893 | 200 µg | $120.00 | 5 | |
作为一种针对组蛋白甲基转移酶 SUV39H1 的抑制剂,Chaetocin 可以间接影响 Periphilin 1 在染色质组织中的作用。 |