PAF Acetylhydrolase Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ginkgolide A | 15291-75-5 | sc-205705 sc-205705A sc-205705B sc-205705D sc-205705C | 10 mg 25 mg 250 mg 1 g 500 g | $67.00 $159.00 $406.00 $1108.00 $679.00 | 2 | |
Ginkgolide B, a terpenoid constituent of Ginkgo biloba, is a known PAF receptor antagonist. By blocking PAF receptors, it indirectly enhances the activity of PAF acetylhydrolase by reducing the level of PAF available for receptor binding, thus promoting the hydrolysis of PAF. | ||||||
1-Linoleoyl Glycerol | 2258-92-6 | sc-220470 sc-220470A | 1 mg 5 mg | $33.00 $147.00 | ||
1-Linoleoyl Glycerol acts as a selective substrate for paf acetylhydrolase, showcasing unique interactions that enhance its hydrolytic activity. This compound influences lipid metabolism by modulating the enzymatic breakdown of bioactive phospholipids, thereby impacting cellular signaling pathways. Its distinct structural features facilitate specific binding to the active site of the enzyme, promoting efficient catalysis and influencing reaction kinetics in lipid-mediated processes. | ||||||
SB 225002 | 182498-32-4 | sc-202803 sc-202803A | 1 mg 5 mg | $35.00 $100.00 | 2 | |
SRI 63-072 acts as a potent enhancer of PAF acetylhydrolase activity by stabilizing the enzyme's active form, thereby increasing its capacity to hydrolyze PAF. | ||||||
Tetrakis(decyl)ammonium bromide | 14937-42-9 | sc-251193 | 10 g | $138.00 | ||
Lyso-PAF serves as a substrate for PAF acetylhydrolase, and its presence stimulates the enzyme's activity as the enzyme catalyzes its acetylation to form PAF. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $65.00 $262.00 | 1 | |
Calcium chloride increases intracellular calcium levels, which can enhance the activity of PAF acetylhydrolase as the enzyme requires calcium ions for its optimal activity. | ||||||
ET-18-OCH3 | 77286-66-9 | sc-201021 sc-201021A sc-201021B sc-201021C sc-201021F | 5 mg 25 mg 50 mg 100 mg 1 g | $109.00 $427.00 $826.00 $1545.00 $3682.00 | 6 | |
As a synthetic alkyl-lysophospholipid, Edelfosine can indirectly enhance PAF acetylhydrolase activity by competing with PAF for binding to cells, thus decreasing PAF's cellular effects and increasing its availability for hydrolysis. | ||||||
WEB-2086 | 105219-56-5 | sc-201007 sc-201007A | 1 mg 5 mg | $100.00 $163.00 | 13 | |
WEB 2086 is another PAF receptor antagonist that allows for the increased activity of PAF acetylhydrolase by minimizing PAF-receptor interactions, favoring PAF breakdown. | ||||||
Miltefosine | 58066-85-6 | sc-203135 | 50 mg | $79.00 | 8 | |
Miltefosine, a phospholipid analog, can increase PAF acetylhydrolase activity by competitively inhibiting PAF receptor and reducing PAF-mediated responses. | ||||||
Seratrodast | 112665-43-7 | sc-201352 sc-201352A | 10 mg 50 mg | $67.00 $373.00 | ||
Modipafant, as a PAF receptor antagonist, indirectly augments PAF acetylhydrolase function by preventing PAF from eliciting its biological effects, leading to increased hydrolysis. | ||||||
Statil | 72702-95-5 | sc-361367 | 100 mg | $235.00 | 1 | |
CV-3988 is a PAF receptor antagonist that can enhance the hydrolytic function of PAF acetylhydrolase by reducing the biological actions of PAF. | ||||||