p35 Inhibitors
Items 1 to 10 of 26 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
Roscovitine (CAS 186692-46-6) is a chemical compound known for its inhibitory action on p35, a protein involved in regulating cell cycle progression and cell proliferation. By targeting p35, Roscovitine hinders specific cellular processes and shows potential significance in research and scientific studies related to cellular biology and molecular mechanisms. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine acts as a potent p35 inhibitor by selectively binding to the active site through hydrogen bonding and hydrophobic interactions. Its complex structure allows for unique conformational flexibility, enabling it to modulate protein-protein interactions effectively. The compound's ability to interfere with kinase signaling pathways is attributed to its competitive inhibition, which alters phosphorylation dynamics and downstream cellular responses, impacting various regulatory networks. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $58.00 $188.00 $884.00 | 10 | |
GSK-3 Inhibitor IX functions as a selective p35 inhibitor, engaging in specific electrostatic interactions that stabilize its binding to the enzyme's active site. This compound exhibits unique kinetic properties, characterized by a rapid association and slower dissociation, enhancing its inhibitory efficacy. Its structural features facilitate unique allosteric modulation, influencing conformational changes in GSK-3, thereby impacting downstream signaling cascades and cellular processes. | ||||||
Kenpaullone | 142273-20-9 | sc-200643 sc-200643A sc-200643B sc-200643C | 1 mg 5 mg 10 mg 25 mg | $61.00 $153.00 $231.00 $505.00 | 1 | |
Kenpaullone acts as a selective p35 inhibitor, demonstrating a unique ability to disrupt protein-protein interactions crucial for cell cycle regulation. Its binding affinity is influenced by hydrophobic interactions and hydrogen bonding, which stabilize its complex with the target protein. The compound exhibits distinct reaction kinetics, with a notable preference for specific conformations that enhance its inhibitory action, ultimately affecting cellular signaling pathways and regulatory mechanisms. | ||||||
10Z-Hymenialdisine | 82005-12-7 | sc-360987 | 500 µg | $210.00 | ||
10Z-Hymenialdisine functions as a p35 inhibitor, showcasing a remarkable capacity to modulate enzymatic activity through its unique structural conformation. Its interactions are characterized by a combination of van der Waals forces and electrostatic interactions, which facilitate selective binding to target proteins. The compound's reactivity is influenced by its steric properties, allowing it to engage in specific molecular pathways that alter cellular dynamics and regulatory networks. | ||||||
Indirubin | 479-41-4 | sc-201531 sc-201531A | 5 mg 25 mg | $114.00 $525.00 | 4 | |
Indirubin acts as a p35 inhibitor, exhibiting a distinctive ability to disrupt protein-protein interactions through its planar structure, which enhances π-π stacking with aromatic residues. This compound's unique hydrogen bonding capabilities enable it to stabilize transient conformations of target proteins, influencing their functional states. Additionally, its lipophilic nature allows for efficient membrane permeability, impacting cellular signaling pathways and regulatory mechanisms. | ||||||
Aminopurvalanol A | 220792-57-4 | sc-223775 sc-223775A | 1 mg 5 mg | $51.00 $118.00 | ||
Aminopurvalanol A functions as a p35 inhibitor, characterized by its ability to selectively modulate enzyme activity through specific interactions with active site residues. Its unique conformation facilitates the formation of stable complexes, altering reaction kinetics and enhancing binding affinity. The compound's polar functional groups contribute to solubility in various environments, allowing it to engage in diverse molecular interactions that influence cellular dynamics and regulatory networks. | ||||||
SNS-032 | 345627-80-7 | sc-364621 sc-364621A | 5 mg 10 mg | $169.00 $262.00 | ||
A potent and selective CDK2/7/9 inhibitor that also affects CDK5 activity. | ||||||
Indirubin-3′-monoxime | 160807-49-8 | sc-202660 sc-202660A sc-202660B | 1 mg 5 mg 50 mg | $79.00 $321.00 $671.00 | 1 | |
Indirubin-3'-monoxime acts as a p35 inhibitor, distinguished by its capacity to disrupt protein-protein interactions critical for cellular signaling. Its structural features enable it to engage in hydrogen bonding and π-π stacking with target proteins, influencing conformational changes that affect enzymatic activity. The compound's hydrophobic regions enhance membrane permeability, while its unique electronic properties facilitate rapid reaction kinetics, impacting downstream signaling pathways. | ||||||
5-Iodo-indirubin-3′-monoxime | 331467-03-9 | sc-221030 | 1 mg | $82.00 | ||
5-Iodo-indirubin-3'-monoxime functions as a p35 inhibitor, characterized by its ability to modulate specific enzymatic pathways through selective binding. The compound's unique halogen substitution enhances its electrophilic character, promoting nucleophilic attack in target interactions. Its planar structure allows for effective π-π interactions, while the presence of electron-withdrawing groups influences reactivity and stability, leading to distinct kinetic profiles in biochemical assays. | ||||||