P2Y13 Activators
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2-Methylthio-ADP trisodium salt | 475193-31-8 | sc-203464 | 10 mg | $838.00 | 5 | |
2-Methylthio-ADP trisodium salt is a potent agonist of the P2Y13 receptor, exhibiting unique binding characteristics that enhance its interaction with G-protein coupled pathways. Its structural modifications facilitate specific molecular recognition, leading to distinct downstream signaling cascades. The compound's reactivity profile allows for rapid engagement with cellular targets, influencing various physiological processes. Its role in modulating receptor activity provides valuable insights into purinergic signaling dynamics. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine may upregulate P2Y13 expression by inducing genomic DNA demethylation, particularly in the promoter region of the P2Y13 gene, thereby enhancing transcription initiation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A (TSA) could increase P2Y13 expression by inhibiting histone deacetylase, leading to hyperacetylation of histones near the P2Y13 gene, resulting in a more transcriptionally active chromatin state. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Vorinostat may stimulate P2Y13 expression by preventing deacetylation of histones, thereby maintaining a chromatin configuration that permits the binding of transcription machinery to the P2Y13 gene promoter. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
By serving as an HDAC inhibitor, valproic acid could elevate P2Y13 levels through enhanced acetylation of histones associated with the gene, promoting transcriptional activation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid could directly stimulate expression of P2Y13 by binding to retinoic acid receptors that function as transcription factors and interact with the P2Y13 promoter region to increase gene transcription. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin may elevate P2Y13 synthesis by increasing intracellular cAMP, which in turn activates protein kinase A (PKA) and leads to the phosphorylation of CREB, a transcription factor that could enhance P2Y13 gene transcription. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
By activating PPARγ, rosiglitazone could directly induce P2Y13 expression through PPAR response elements in the P2Y13 gene promoter, initiating transcription. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Metformin could enhance the transcription of P2Y13 through the activation of AMPK, which may initiate a cascade of transcriptional events, potentially involving upregulation of P2Y13 as part of cellular energy homeostasis. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol may promote P2Y13 expression by activating sirtuin 1, which can lead to deacetylation of transcription factors or co-regulators involved in the transcriptional activation of the P2Y13 gene. | ||||||